Madlen Hubert

Researcher at Department of Pharmacy; Molecular Pharmaceutics

E-mail:
madlen.hubert@farmaci.uu.se
Visiting address:
Biomedicinskt Centrum BMC, Husargatan 3
Postal address:
Box 580
751 23 UPPSALA

Short presentation

I am an Associate Professor in Pharmaceutics and my research integrates rational formulation design, biophysics, and molecular biology to understand how therapeutics and target systems interact. I am currently co-leading a work-package within GENEGUT, a Horizon Europe Framework Program consortium, to develop RNA therapy to treat ileal Crohn’s disease and I coordinate a projects on oral delivery of antibiotics funded by the Uppsala Antibiotic Center.

Keywords

  • biomaterials
  • cell biology
  • cell culture
  • confocal microscopy
  • drug delivery
  • enabling formulations
  • fluorescence microscopy
  • intestinal organoids
  • lipid based formulations
  • nanoparticles
  • rna therapeutics
  • self-assembly

Research

I have a background in pharmacy and a PhD in Pharmaceutical Sciences from the University of Otago, New Zealand, with expertise in drug delivery and in vitro models for formulation testing. My research explores lipid-based nanoparticles for oral delivery of challenging therapeutics. I am particularly interested in studying the interactions of nanoparticle with target tissues using a combination of cell-based assays, biophysical approaches as well as advanced microscopy techniques. Additionally, I focus on developing more clinically relevant in vitro models based on human intestinal organoids as a powerful tool in drug development.

Publications

Recent publications

All publications

Articles

Madlen Hubert

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