Bioorganic Chemistry
Syllabus, Bachelor's level, 1KB406
- Code
- 1KB406
- Education cycle
- First cycle
- Main field(s) of study and in-depth level
- Chemistry G1F, Technology G1F
- Grading system
- Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
- Finalised by
- The Faculty Board of Science and Technology, 18 March 2008
- Responsible department
- Department of Chemistry - BMC
Entry requirements
Basic Chemistry, 10 credits and Organic Chemistry, 5 credits or equivalent.
Learning outcomes
Afterof the course, the student should be able to
- use rules for description of the structure and stereochemistry of bioorganic compounds
- relate the chemical structure of biomolecules to properties such as solubility binding ability (hydrogen bond ability, lipophilicity, hydrophilicity), chirality
- correlate the chemical structure of biomolecules to reactivity
- discuss similarities and differences between transformations of biomolecules in living systems (aquatic environment) and in vitro, e.g. industrial synthesis
- describe how some course concepts are applied within the biomolecular - and pharmaceutical fields
- give examples of how chemical properties and reactivity can influence environmental and economical decisions
- discuss appropriate chromatographic methods for determination of organic compounds
- Plan and carry out laboratory work in a correct and safe manner and carry out simpler risk and security assessments
Content
Organic Chemistry of biologically relevant compound classes: Carbohydrates, lipids, amino acids and peptides, nucleic acids. Reaction mechanisms to build and degrade carbon compounds. Examples of catalytic reactions: Acid -base catalysis, enzymatic catalysis, metal catalysis (in biological systems). Organic-chemical reactions in water. Comparison between synthesis in biological systems and industrial synthesis. The fundamentals of chromatographic separation. Analysis of biomolecules e g peptides, nucleic acids by chemical and spectroscopic methods.
Instruction
Lectures, problem solving sessions and laboratory work.
Assessment
Written examinations are organised at the end of the course and/or during the course and corresponds to 3 credits. The laboratory sessions correspond 2 credits. To pass final grades it is required that all parts have been assessed passed. The final grade is a weighted average of the results from the written examination, the laboratory work and projects.