General provisions

Substituting and corresponding earlier the 3FM042 of course. 1.5 credits (hp) correspond to 1 credit point (p) according to earlier study regulation.

Entry requirements

The general rules stated by the Curriculum Committee of the Faculty of Pharmacy (see programme curriculum). For entry to the separate course, students are required to fulfil the basic requirements for university entry and to have passed the Bachelor of Pharmaceutical Science degree, 80 points, or have the equivalent knowledge acquired in a medical, veterinary science, dental, pharmaceutical, scientific or foreign degree course.

Learning outcomes

On completion of the course, the student should be able to:

- describe the organisation at prokaryotic and eukaryotic organisms and at well-known viruses and plasmids of the genes and the genomes

- describe how the genetic information is turned to RNA and protein in prokaryotic and eukaryotic cells and how the genomes replikeras

- describe how change in the genome takes place via mutations and recombination processes and how injuries in DNA are repaired.

- describe mechanisms for gene regulation in prokaryotic and eukaryotic organisms

- describe different methods that can be used in genetic and molecular biological research activity such as PCR, hybridisation and nucleic acid sequencing

- plan and carry out cloning experiments in escherichia coli

- describe horizontal and vertical gene transfer at bacteria and higher organisms

- calculate genetic distances on a chromosome and förklar how one can identify different pathogens by means of different markers

- calculate the risk for origin of specific hereditary diseases in a population by means of Hardy-Weinbergs law

- describe symptom, treatment and diagnostics of certain hereditary diseases

- describe how one be able to analyse the inheritance importance for the origin of multifactorial diseases such as diabetes and cancer.

Content

Course aims to provide knowledge about how genome govern cells' functions, how these are inherited and how genetic molecules vary. This includes the use of molecular biological, genetic, biochemical and bioinformatic tools and development of drug by means of this knowledge.

Instruction

Teaching be informed in the form of lectures, group assignments and laboratory sessions.

Compulsory parts of the course:

Start of the course and participation in laboratory sessions.

Assessment

Examination takes place at the end of the course. For a Pass grade in the course is required apart from pass test (examination code), pass results of compulsory parts (examination code). Obligatory portions of the course may be completed or re-taken when the same course is offered again if, and only if, the course is not full. For the course of the autumn semester, re-examinations in January are organised, and for the course of the spring semester, re-examinations in August are organised. Each student has the right to in all 6 examination sessions i.e. one test and five re-examinations.