Entry requirements

General entrance qualification 13 Chemistry 30 credits or equivalent Cell Biology 22.5 credits or equivalent

Learning outcomes

The course should provide good knowledge of cellular interactions during formation of various types of tissues and the cellular specialisation with a focus on man and model organisms. The AIMS of the COURSE: The student is expected on completion of the course to: • Be able to account for the fertilisation process, the gastrulation, embryonic development and to describe the development of vertebrate organs and how these processes are governed. • Be able to account for how signal transduction governs cell determination and differentiation. • Be able to account for the structure and appearance of different tissues. • Be able to account for available methods to study connections between genotype and phenotype in different model organisms. • Be able to discuss ethical aspects on the application of cloning and transgenic techniques. • Be able to account for the normal regulation of cell division, cell death and the origin of cancer. • Be able to account for the theory behind practical parts, independently formulate and carry out experiments and be able to compile and interpret results in both written and oral form. • Be able to search, compile, present and review critically cell and tissue biology information.

Content

Embryology Fertilisation, early embryo development and the development of the different organ systems, malformations and ethics. Tissue biology The social cell: cell adhesion, extracellular matrix, specialised cells, tissues, growth factors and embryonic induction and morphogenesis, germ cell, somatic cell, cell differentiation during the embryogenesis, transcriptional control and signal transduction, stem cells, model organisms for studies of the development of the cell and tissues, basic genetics and genetic analysis, transgenic - and gene elimination, the formation of cancer and tumour cells, angiogenesis and blood coagulation. Laboratory work: microscopy of tissues, heparin, integrin signalling. Professional training.

Instruction

Lectures, seminars, demonstrations, mikroscopy - and computer exercises, applied laboratory sessions, supported self-learning and seminar presentations. At the group assignments, the students should independent and in groups acquire, review, compile and present (orally and written) information from a given task. The students should prepare opposition on another group presentation. Deeper teaching in the form of lectures and practical exercises are given in library science, oral and written presentation techniques. The students' attendance is compulsory at seminars, microscopy, group assignments, professional training and at all parts in connection with the laboratory sessions.

Assessment

Possibility to supplement failed laboratory course can be given at the earliest at next course and only in case of a vacancy. Students who have not passed the examination have the right to take the examination 4 additional times (= total 5 examinations). If special circumstances apply, the programme committee can admit additional examination. Submission of so called blank exam is counted as an examination.