Analytical Chemistry with Data Analysis and Chemometrics
Syllabus, Bachelor's level, 1KB103
- Code
- 1KB103
- Education cycle
- First cycle
- Main field(s) of study and in-depth level
- Chemistry G1F, Technology G1F
- Grading system
- Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
- Finalised by
- The Faculty Board of Science and Technology, 28 October 2014
- Responsible department
- Department of Chemistry - BMC
Entry requirements
Basic courses in chemistry about at least 30 credits.
Learning outcomes
For completion of the course the student shall be able to:
- identify and describe the steps that are included in a complete analytical procedure
- account for common sampling techniques for inorganic and organic compounds and calculate necessary sample size and number of samples in connection with sampling
- report for and use decomposition - and pretreatment techniques for inorganic and organic compounds
- report for and use analytical methods based on liquid - and gas chromatographic methods, electro-analytical methods, methods based on atomic and molecular spectrometry and mass spectroscopy and be familiar with appropriate use for these method
- explain the concept uncertainty; identify and describe different contributions to the uncertainty and calculate the combined uncertainty
- apply statistical inference in the form of confidence intervals, t-test, F-test, one-way analysis of variance and Chi-square test in chemical problems
- carry out simple linear regression with calculation of confidence intervals for slope, intercept and predictions and calculate and interpret the correlation coefficient
- calculate and present practically received analysis results in writing and use statistical methods according to above to assess and ensure the quality
- describe the principles for experimental design with more than one influencing factor and state how multivariate data can be utilised for classification and calibration
- apply the above within drugs and the manufacturing industry
Content
Analytical methods including quality assurance. Sampling and sample preparation. Chromatographic methods as GC and LC. Electroanalytical techniques (potentiometric and voltammetric techniques). Atomic spectroscopy (AAS, AES). Molecular spectroscopy (UV/Vis, NIR, fluorescence, chemiluminescence). Mass spectrometry. Applications of univariate statistics. Quality assurance in analytical work. Introduction to experimental design for modelling and optimisation. Introduction to multivariate methods for calibration and classification. Laboratory work: The Laboratory work enlightening atomic spectroscopy, potentiometry, gas chromatography and liquid chromatography . Computer exercises: Computer exercises with Excel for statistical analysis of measurement. Chemometrical applications with Minitab and Unscrambler as robustness tests, classification, multivariate calibration.
Instruction
Lectures, lessons, laboratory work and computer exercises.
Assessment
Written examination during and/or at the end of the course, equivalent 6 credits. For approval, passed laboratory course and passed assignments equivalent to 4 credits are also required . The final grade corresponds to a weighed average of the results from the written examination and the laboratory work.
Other directives
This course cannot be included in a degree together with the course 1KB105 Analytical Chemistry I
Reading list
- Reading list valid from Spring 2022
- Reading list valid from Autumn 2019
- Reading list valid from Autumn 2017
- Reading list valid from Spring 2015
- Reading list valid from Autumn 2012
- Reading list valid from Autumn 2011
- Reading list valid from Autumn 2010
- Reading list valid from Autumn 2008, version 2
- Reading list valid from Autumn 2008, version 1