General provisions

Substituties and corresponds 3FX009 or 3FX800, Toxicology B.

Entry requirements

30 credits in bioscience (e.g. biochemistry, cell biology, physiology, pharmacology, molecular biology, microbiology).

Learning outcomes

After the course, the students should be familiar with different modes of action behind the potential toxic, carcinogenic, teratogenic and reproduction toxicological effects of drugs and other chemicals. The students should also have good awareness of how toxicological risk assessment and safety assessment is practised and be able to utilise this knowledge to assess reported clinical adverse drug reactions and environmental related health risks in man. On completion of the course, the student should have obtained a general knowledge about applied toxicology.

Content

The course will mainly treat basic toxicology and toxicological risk assessment/safety assessment. The following parts will then be included: Toxicological fundamental concepts; Toxicological aspects on absorption, distribution and metabolism; Mechanisms for substances adverse effects in larger organ systems; Genetic toxicology; Chemical carcinogenesis; Reproduction toxicity; Embryotoxicity/teratogenicity; Immunotoxicity; Toxicological risk assessment/safety assessment.

Instruction

Teaching is given as lectures and seminars. Compulsory parts of the course: Course introduction, participating in seminars and advanced assignment and presentation.

Assessment

Examination (individual written examination) takes place at the end of the course. To pass the course is required, apart from passed examination (examination code), passed results of compulsory parts (examination code). Possibility to supplement failed compulsory part can be given at the earliest at next course and only in case of a vacancy. Each student has the right to in all six examinations i.e. one examination and five re-examinations.