Entry requirements

Basic Chemistry.

Learning outcomes

After having completed the course, the student should to be able to:

• apply rules for the description of structure and stereochemistry of organic compounds
• relate chemical structure to properties such as melting point, boiling point, viscosity, chirality, acid strength, interaction with light (e. g., colour)
• give examples for the relationship between structure and functionality in applications of technical interest
• use knowledge on chemical reaction types such as substitution, addition, and elimination, as well as the Lewis acid-base concept with its relationship to reactivity of organic compounds
• explain the terms nucleophile and electrophile and give examples for the most common reactions of functional groups
• keep a record of laboratory experiments
• describe the application of some of the concepts of the course in biomolecular science and in medicinal chemistry
• give examples for the impact of chemical properties and reactivity on environmental and economic decisions

Content

Various models for the description and understanding of the structure of organic molecules (functional groups, isomerism, chirality and conformers). Consequences of binding and structure for molecular properties. Inter- and intramolecular interactions. Reaction types: Substitution, elimination, addition, radical reactions, reaction kinetics, catalysis. Importance of stereochemistry in biological systems. Information on spectroscopic methods in organic chemistry (UV, IR, MS, NMR). Laboratory exercises: Organic syntheses exemplifying theory, synthtetic techniques, purification and separation as well as structural characterisation using spectroscopic methods.

Instruction

Lectures, seminars, and laboratory work. Laboratory work and related presentations are mandatory.

Assessment

Written examination is arranged at the end of the course, corresponding to 3 HE credits. The laboratory work including presentations is valued as 2 HEcredits. The final grade is the weighted grade of both theoretical and experimental work.

Other directives

The course can not be included in higher education qualification together with 1KB472 Introductory Organic Chemistry.