Entry requirements

Participation in Chemical Principles I/Basic Chemistry, 10 credits.

Learning outcomes

After completing the course, the student should be able to:

• identify different classes of biomolecules and structures, explain fundamental relationships between their structure and function and describe the principal organisation of prokaryotic and eukaryotic cells
• describe the molecular principles of catalysis and regulation of enzyme activity in living cells.
• describe transport and signal processing in living cells
• describe energy metabolism in living cells
• plan, perform and document protein separation and analysis as well as enzyme kinetic measurements in a correct and safe manner. Explain methods and give oral / written account for the experimental results. Perform basic risk and safety assessments
• explain the chemical / biological background to everyday biological phenomena and describe the role of biochemistry for humans, environment and society

Content

Structure of prokaryotic and eukaryotic cells. Bioenergetics. Biomolecules. The central dogma. Enzyme mechanisms and kinetics. Biological membranes. Signal transduction. Different types of receptors. Overview of energy metabolism. Principles of energy conversion in cellular systems. Chromatographic, electrophoretic and simple enzyme kinetic methods for the purification and analysis of biomolecules.

Instruction

Lectures, problem solving sessions and laboratory work. Project as group work.

Assessment

Written exam (5 credits), laboratory work (4 credits) and oral examination of the project (1 credit). The final grade corresponds to a weighted average of the results from the written examination and the laboratory work.

Other directives

This course cannot be included in a degree together with the course 1KB408 (Biochemistry I).