Advanced Techniques in Molecular Medicine
Syllabus, Master's level, 3MG323
- Code
- 3MG323
- Education cycle
- Second cycle
- Main field(s) of study and in-depth level
- Medical Science A1N, Molecular Medicine A1N
- Grading system
- Fail (F), Sufficient (E), Satisfactory (D), Good (C), Very good (B), Excellent (A)
- Finalised by
- The Master Programmes Board of the Faculty of Medicine, 11 April 2024
- Responsible department
- Department of Immunology, Genetics and Pathology
Entry requirements
BSc, Bachelor's degree, equivalent to a Swedish degree of at least 180 credits in biochemistry/chemistry, biology, biomedicine/medicine, biotechnology, cell/molecular biology, genetics, life science, medical sciences or a similar field of study giving relevant knowledge in bio-/chemistry, cell- and molecular biology as well as genetics. Knowledge of and experience in laboratory work. Proficiency in English equivalent to the Swedish upper secondary course English 6.
Learning outcomes
Knowledge and understanding
On completing the course, the student shall demonstrate the ability to:
- formulate and process scientific questions theoretically and practically.
- account for and evaluate current methods and techniques within the research field.
Competence and skills
On completing the course, the student shall demonstrate the ability to:
- argument for the choice of appropriate laboratory techniques.
- apply the relevant methodologies and technologies in practice.
Judgement and approach
On completing the course, the student shall demonstrate the ability to:
- compile, critically analyse and evaluate research results and present these both orally and in writing.
- explain how to work with an ethical and scientific approach.
Content
The course focuses on technologies relevant to molecular medicine and physiological processes. It covers elements from genomes to cellular interactions. Examples of methods that will be covered are: genotyping at monogenetic and complex diseases, identification, isolation and functional analysis of genes, advanced PCR techniques, detection of mutations, DNA/RNA/protein-based diagnostics. DNA techniques within diagnostics and functional genome analysis will include RNA-sequencing technology for gene expression, comparative genomics, tissue expression and current methods for analysis of epigenetic regulatory mechanisms such as chromatin immunoprecipitation (ChIP) and ATAC-sequencing. The techniques and equipment for large-scale trials within genotyping and sequencing are included. In addition, molecular cloning and induction of genome modification with CRISPR is discussed in this course.
Instruction
Instruction is provided in English in the form of lectures and mandatory seminars, laboratory exercises, computer practicals and other theoretical and practical exercises such as problem-oriented exercises and presentations related to current research fields. A joint seminar series for Master's programmes is included.
Assessment
Modes of assessment
The course concludes with a written assignment in form of a project report, final oral presentation and continuous assessment of compulsory course components.
Exceptions to modes of assessment
If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the University's disability coordinator.
Requirements for a passing grade
To achieve a passing grade for the course the student requires completed laboratory practicals, a passing grade on the written assignment and on the oral presentations plus a pass for active participation in all compulsory course elements such as seminars.
Reading list
No reading list found.