Forskning vid Uppsala universitet

Forskningsprojekt från 2012-01-01 till 2012-12-31

We have two times previously been organizing a biannual conference in Uppsala with support from Vetenskapsrådet. The first conference, ?Neurodegenerative disorders: immunotherapy and biomarkers? was held ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Fibrillar alpha-synuclein in Lewy bodies is the main hallmark in brains of patients with Parkinson´s disease and some other brain disorders. However, recent studies indicate that oligomers or protofibrils ...

Forskningsprojekt från 2017-07-01 till 2020-06-30

Further investigation of the neural underpin of cognitive aging, and associated reserve factors is much warranted. In this 3-year post-doctoral project, 2 years will be spent at Colombia University, New ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Hip fractures annually affect almost 20,000 patients in Sweden. In about 2,000 patients with displaced femoral neck fractures insertion of a total hip arthroplasty (THA) is the best available treatment ...

Forskningsprojekt från 2021-01-01 till 2023-12-31

We recently made three discoveries related to acquired Loss Of chromosome Y (LOY) in blood of adult/aging men. LOY is associated with: a) shorter survival and increased mortality from cancer; b) Alzheimer ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Mutations in the genes for the amyloid precursor protein (APP) and the presenilins cause early-onset, inherited forms of Alzheimer’s disease (AD). We have previously identified and characterized two different ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

Alzheimer´s disease (AD), dementia with Lewy bodies (DLB) and Parkinson´s disease (PD) are the most common neurodegenerative disorders caused by aggregation of pathological proteins in the brain. In AD ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

Nutrition, i.e. the interaction between food intake, metabolism and body composition, is a main denominator for health, functionality and longevity. Nutrition has strong implications on age-related cognitive ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The over-all purpose of this project is to improve clinical PET imaging of amyloid-beta (Abeta), such that the technique can be used to monitor disease progression and therapeutic efficacy of drug candidates ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

Our recent analysis shows that de novo somatic (acquired during lifetime) genetic aberrations in the genome of normal cells accumulate with age, are common in elderly, and thus likely contribute to the ...