Injicerbara, resorberbara och last bärande implantat för hårdvävnadsrekonstruktion

Tidsperiod: 2012-01-01 till 2014-12-31

Projektledare: Håkan Engqvist

Finansiär: Vetenskapsrådet

Bidragstyp: Projektbidrag

Budget: 2 400 000 SEK

Due to a rapidly increasing amount of elderly in our society, musculoskeletal problems are a growing area. The costs related to the problems are enormous and new treatment methods are needed. Minimal invasive methods using injectable biomaterials to reduce the surgery time and aid the patient to recover faster with a longer lasting rehabilitation is one growing treatment. So far the number of injectable biomaterials for the hard tissue treatment is limited to either load bearing inert materials or resorbable and mechanically weak materials. The project?s objective is to develop a new biomaterial platform, that can be injected, harden in vivo with adequate mechanical properties and on the same time be resorbable and in the future possible to load with active ingredients. The concept is to use resorbable ceramics and polymer to form a hybrid systems, via i.e. Ca-salts and resorbable polymers. By tailoring the chemical reactions to allow the setting reaction to form both a ceramic and a polymer network an optimal ortopaedic material can be formed. The proposed concept is new, far-reaching and stretches the current concepts of orthobiologics. The impact of the international research community of such a material concept will be large and will open up for new innovations in a high priority industrial area. The aim is that within four years have tested the concept in bench and in vitro tests.