Grafenbaserad fälteffektkomponent för jonselektiv detektering
Tidsperiod: 2015-01-01 till 2018-12-31
Projektledare: Shi-Li Zhang
Budget: 3 200 000 SEK
The proposed project aims at exploring Graphene field-effect devices as Ion-Selective Sensors (GISS). The GISS are configured in the form of a novel device structure capable of simultaneous operation in transistor- and capacitor-mode in electrolytes. The research concerns studying diffusion and adsorption of ions or DNA molecules inside the so-called electrical double layer (EDL), understanding noise generation associated with these kinetic processes and identifying means to improve the sensor performance. The hydrophobicity of graphene will be exploited for selective sensing and the role of the grain boundaries (GB) present in graphene will be investigated. Thus, the purpose is to generate new knowledge towards substantially improving the fidelity of field-effect electronic biosensors. For a successful project with the GISS, we will: 1) understand the dispersion behaviour of the EDL up into the high-MHz regime and increase the sensitivity by extending the probing depth into the electrolyte beyond the static EDL; 2) determine whether low-frequency noise of the EDL is the fundamental limit for GISS in particular and ISFET in general, and apply this knowledge for attaining a high signal-to-noise ratio with GISS; 3) exploit the hydrophobic nature of graphene and study its GB leading to smart (graphene) surface functionalization schemes towards selective sensing with regard to pH, selective detection of physiologically relevant ions, i.e. Na+, K+ and Ca++, as well as DNA binding.