Nya implantatmaterial designade för barn

Tidsperiod: 2018-01-01 till 2021-12-31

Projektledare: Håkan Engqvist

Finansiär: Vetenskapsrådet

Bidragstyp: Projektbidrag

Budget: 3 600 000 SEK

Severe trauma or illness can result in complex cranial defects. This is particularly difficult in a growing skull bone in children. This results in permanent and very difficult to treat defects with severe suffering for the patients and high costs for society. The purpose of the research program is to develop a new implant design for reconstruction of complex defects in children. The aim is to after the program end have documented scaffold design in first in vitro studies. The research strategy involves the use of 3D printing to achieve a positive replica of the skull defect (e.g. from CT images). The replica will be used as mold for manufacturing an implant using new moldable bioceramic formulations combined with implant design that can “adobt” to the skull bone. The proposed concept is new, far-reaching and stretches the current concepts of scaffold design and regenerative medicine. So far no viable clinical solution has been found for healing of complex in children. The impact of the international research community of such a material concept will be large and will open up for new innovations and future clinical methods.