Gunilla Enblad's project on lymphomas and prostate cancer

Biology of diffuse large B-cell lymphoma

Gunilla Enblad, Mattias Berglund, Jamileh Hashemi, Charlott Mörth, Amal Abu Sabaa, Antonis Valachis, Gustav Gammelgård, Tania Nicolaescu, Emma Pettersson

In our research we study the biological background for the origin and growth of the tumour. We are using the U-CAN material to study tumour material and serum and plasma proteins to elucidate the biology of the disease. The project is a collaboration within Uppsala University with Rose-Marie Amini, Eva Baecklund, Panagiotis Baliakas, Mats Hellström

Development of new therapies

Gunilla Enblad, Hans Hagberg, Gustav Gammelgård, Daniel Molin, Mats Hellström

Another aim is to develop new therapies for patients who do not respond to the standard treatments used today. We are for instance working with a new strategy where genetically modified T cells, CAR T cells, a type of white blood cell, are used to eradicate the tumour cells. The project is performed in collaboration with Magnus Essand and Angelica Loskog.

Clinical and biological studies of Hodgkin lymphoma

Daniel Molin, Gunilla Enblad, Ingrid Glimelius, Peter Hollander, Ingemar Lagerlöf, Ninja Övergaard

The aim is to increase the knowledge of the interaction between the tumour cells and the microenvironment in Hodgkin lymphoma, and how this knowledge can be used to develop new treatments. Furthermore, our aim is to study FDG-PET in relation to the microenvironment and to perform clinical studies on patients with Hodgkin lymphoma. Lastly, our aim is to study late effects of the treatment and how they can be avoided. The project is performed in collaboration with Rose-Marie Amini, Gustaf Ljungman and Annika Englund.

Clinical and biological studies of prostate cancer

Ingrida Verbiene, Silvia Johansson and Gunilla Enblad

The projects involve different aspects of radiotherapy for patients with prostate cancer and how the effects can be measured and described. We have evaluated patients with localised prostate cancer, treated with proton beam therapy or brachytherapy and we study the biology of prostate cancer after different schedules of radiotherapy.