Biocompatibility
Biocompatibility is a key aspect in the development of materials for biomedical applications.
Biocompatibility - a key aspect in the development of nanomaterials for biomedical applications
Biocompatibility is a key aspect in the development of materials for biomedical applications. It comprises the ability of the material to perform its desired function with respect to a medical therapy, the absence of undesirable effects and the generation of the most beneficial cellular or tissue response.
Since biological systems present properties guided in the nanometer scale, the potential of nanomaterials in biomedical sciences represents an exciting field with endless opportunities of obtaining novel biomaterials with improved biocompatibility.
Our research activities focus on the use of application-oriented biocompatibility studies to evaluate the impact of nanomaterial design or modifications on the bioactivity of the material and the response of biological systems.
Our current projects in this research area aim to address unmet needs in chronic wound care. We investigate the use of cellulose nanofibrils as a core wound dressing for the incorporation of bioactive molecules (e.g. growth factors, host defense peptides) and evaluate its ability to modulate the chronic wound environment and promote the resolution of these hard-to-heal wounds. Furthermore, we explore the use of cellulose nanofibril-based hydrogels as a matrix for cell therapy in chronic wound care.
Projects
- NanocellSense: A sense and respond nanocellulose-based delivery platform for wound healing, bioactive molecules
- NanoPeptideCare: A new generation of therapeutic platforms for the treatment of chronic wounds: Host defense peptides meet nanocellulose