Läkemedelsformulering
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Publikationer
Ingår i Clinical Pharmacokinetics, s. 109-120, 2024
- DOI för Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals
- Ladda ner fulltext (pdf) av Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals
Ingår i International Journal of Pharmaceutics, 2024
Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates
Ingår i Nature Communications, 2024
- DOI för Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates
- Ladda ner fulltext (pdf) av Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates
Ingår i Biotechnology Journal, 2024
- DOI för The choice of ultra-low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function
- Ladda ner fulltext (pdf) av The choice of ultra-low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function
Epithelial and microbial determinants of colonic drug distribution
Ingår i European Journal of Pharmaceutical Sciences, 2023
- DOI för Epithelial and microbial determinants of colonic drug distribution
- Ladda ner fulltext (pdf) av Epithelial and microbial determinants of colonic drug distribution
Ingår i Clinical Pharmacokinetics, s. 725-735, 2023
- DOI för Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance
- Ladda ner fulltext (pdf) av Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance
Ingår i Computational and Structural Biotechnology Journal, s. 4361-4369, 2023
- DOI för Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
- Ladda ner fulltext (pdf) av Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
Ingår i ACS Nano, s. 14210-14229, 2022
- DOI för Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
- Ladda ner fulltext 1 (pdf) av Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
- Ladda ner fulltext 2 (pdf) av Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
Ingår i European Journal of Clinical Pharmacology, s. 1289-1299, 2022
- DOI för Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range
- Ladda ner fulltext (pdf) av Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range
Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
Ingår i Clinical Pharmacology and Therapeutics, s. 1142-1154, 2022
- DOI för Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
- Ladda ner fulltext (pdf) av Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
Ingår i International Journal of Molecular Sciences, 2022
- DOI för Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
- Ladda ner fulltext (pdf) av Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
Ingår i Pharmaceutical research, s. 1599-1613, 2022
- DOI för High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
- Ladda ner fulltext (pdf) av High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
Ingår i Clinical and Translational Science, s. 2685-2696, 2022
- DOI för Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
- Ladda ner fulltext (pdf) av Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
Ingår i Biomedicine and Pharmacotherapy, 2022
- DOI för Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
- Ladda ner fulltext (pdf) av Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
Ingår i Nucleic Acids Research, 2022
- DOI för Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
- Ladda ner fulltext (pdf) av Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics
Ingår i Pharmaceutical research, s. 1283-1289, 2022
Ingår i British Journal of Clinical Pharmacology, s. 4121-4133, 2022
- DOI för Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity
- Ladda ner fulltext (pdf) av Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity
Ingår i Clinical and Translational Science, s. 221-233, 2022
- DOI för Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial
- Ladda ner fulltext (pdf) av Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial
Ingår i International Journal of Pharmaceutics, 2022
Ingår i Journal of Experimental & Clinical Cancer Research, 2021
- DOI för Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
- Ladda ner fulltext (pdf) av Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
Ingår i iScience, 2021
- DOI för Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
- Ladda ner fulltext (pdf) av Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
Ingår i Advanced Drug Delivery Reviews, s. 289-331, 2021
- DOI för Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
- Ladda ner fulltext (pdf) av Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Ingår i Journal of Pharmaceutical Sciences, s. 388-396, 2021
- DOI för Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1
- Ladda ner fulltext (pdf) av Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1
Ingår i Nature Materials, s. 1043-1044, 2021
Hepatocyte size fractionation allows dissection of human liver zonation
Ingår i Journal of Cellular Physiology, s. 5885-5894, 2021
- DOI för Hepatocyte size fractionation allows dissection of human liver zonation
- Ladda ner fulltext (pdf) av Hepatocyte size fractionation allows dissection of human liver zonation
Ingår i Molecular Pharmaceutics, s. 1792-1805, 2021
- DOI för Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes
- Ladda ner fulltext (pdf) av Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes
Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer
Ingår i THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2021
- DOI för Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer
- Ladda ner fulltext (pdf) av Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer
Ingår i Journal of Pharmaceutical Sciences, s. 239-250, 2021
- DOI för Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
- Ladda ner fulltext (pdf) av Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
Ingår i Clinical Pharmacology and Therapeutics, s. 762-771, 2021
- DOI för Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight
- Ladda ner fulltext (pdf) av Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight
Ingår i Drug Metabolism And Disposition, s. 8-17, 2020
A new opening for orally taken peptide drugs
Ingår i Nature Biomedical Engineering, s. 12-13, 2020
Ingår i Pharmaceutics, 2020
- DOI för Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
- Ladda ner fulltext (pdf) av Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
Cell-type-resolved proteomic analysis of the human liver
Ingår i Liver international, s. 1770-1780, 2020
- DOI för Cell-type-resolved proteomic analysis of the human liver
- Ladda ner fulltext (pdf) av Cell-type-resolved proteomic analysis of the human liver
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
Ingår i Nature Communications, 2020
- DOI för Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
- Ladda ner fulltext (pdf) av Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
Global variability analysis of mRNA and protein concentrations across and within human tissues
Ingår i NAR Genomics and Bioinformatics, 2020
- DOI för Global variability analysis of mRNA and protein concentrations across and within human tissues
- Ladda ner fulltext (pdf) av Global variability analysis of mRNA and protein concentrations across and within human tissues
The Critical Role of Passive Permeability in Designing Successful Drugs
Ingår i ChemMedChem, s. 1862-1874, 2020
Ingår i Pharmaceutical research, 2019
- DOI för A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell))
- Ladda ner fulltext (pdf) av A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell))
A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes
Ingår i Archives of Toxicology, s. 819-829, 2019
- DOI för A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes
- Ladda ner fulltext (pdf) av A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes
Comprehensive drug uptake transporter proteomics and metabolomic profiling of human liver
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, 2019
Experimental approaches to understand intracellular based drug bioavailability
Ingår i Drug Metabolism and Pharmacokinetics, 2019
Image-based quantification of cell debris as a measure of apoptosis
Ingår i Analytical Chemistry, s. 5548-5552, 2019
- DOI för Image-based quantification of cell debris as a measure of apoptosis
- Ladda ner fulltext (pdf) av Image-based quantification of cell debris as a measure of apoptosis
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Ingår i AAPS Journal, 2019
- DOI för Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
- Ladda ner fulltext (pdf) av Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Ingår i Scientific Reports, 2019
- DOI för Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
- Ladda ner fulltext (pdf) av Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
Ingår i Journal of Proteome Research, s. 217-224, 2019
- DOI för Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking
- Ladda ner fulltext (pdf) av Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking
Ingår i Clinical Pharmacology and Therapeutics, s. 525-543, 2019
Ingår i Scientific Reports, 2018
- DOI för Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
- Ladda ner fulltext (pdf) av Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box
Ingår i Drug Metabolism And Disposition, s. 1776-1786, 2018
Ingår i Drug Metabolism And Disposition, s. 387-396, 2018
- DOI för Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
- Ladda ner fulltext (pdf) av Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids
Ingår i Molecular Pharmaceutics, s. 2224-2233, 2018
- DOI för Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids
- Ladda ner fulltext (pdf) av Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids
Ingår i Genome Medicine, 2018
Kontakt
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- Brev- och paketadress: Box 580, 751 23 Uppsala