Gustav Berggrens grupp
![Gustav Berggren i labbet](/images/18.75e37daa18e79b469f438b40/1712564968058/Gustav%20Berggren_966x414.jpg)
Metallproteiner och deras kofaktorer
Vår forskning
Berggrengruppen arbetar inom bio-oorganisk kemi och biofysik, och täcker ett brett spektrum av ämnen relaterade till metallproteiner och deras kofaktorer. Arbetet karakteriseras av ett tvärvetenskapligt tillvägagångssätt som kombinerar synteskemi med klassiska biokemiska och biofysikaliska tekniker. Tonvikten ligger på att förstå samspelet mellan peptiden och den oorganiska kofaktorn i det aktiva sätet, samt att visa på hur denna kunskap kan användas i (bio-)teknologiska tillämpningar.
Gruppmedlemmar
Publikationer
Ingår i Nature Communications, 2024
- DOI för Embedding biocatalysts in a redox polymer enhances the performance of dye-sensitized photocathodes in bias-free photoelectrochemical water splitting
- Ladda ner fulltext (pdf) av Embedding biocatalysts in a redox polymer enhances the performance of dye-sensitized photocathodes in bias-free photoelectrochemical water splitting
Kinetic Modeling of the Reversible or Irreversible Electrochemical Responses of FeFe-Hydrogenases
Ingår i Journal of the American Chemical Society, s. 1455-1466, 2024
Ingår i ACS Catalysis, s. 10435-10446, 2023
- DOI för Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
- Ladda ner fulltext (pdf) av Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
Ingår i ACS Catalysis, s. 9476-9486, 2023
- DOI för Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
- Ladda ner fulltext (pdf) av Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
Ingår i Energy Advances, s. 2085-2092, 2023
- DOI för E. coli-based semi-artificial photosynthesis: biocompatibility of redox mediators and electron donors in [FeFe] hydrogenase driven hydrogen evolution
- Ladda ner fulltext (pdf) av E. coli-based semi-artificial photosynthesis: biocompatibility of redox mediators and electron donors in [FeFe] hydrogenase driven hydrogen evolution
Structural basis for bacterial energy extraction from atmospheric hydrogen
Ingår i Nature, s. 541-547, 2023
- DOI för Structural basis for bacterial energy extraction from atmospheric hydrogen
- Ladda ner fulltext (pdf) av Structural basis for bacterial energy extraction from atmospheric hydrogen
Ingår i Frontiers in Microbiology, 2023
- DOI för Novel concepts and engineering strategies for heterologous expression of efficient hydrogenases in photosynthetic microorganisms
- Ladda ner fulltext (pdf) av Novel concepts and engineering strategies for heterologous expression of efficient hydrogenases in photosynthetic microorganisms
Ingår i ACS Catalysis, s. 1246-1256, 2023
Ingår i Sustainable Energy & Fuels, s. 4967-4976, 2023
- DOI för Synthetic styrene-based bioinspired model of the [FeFe]-hydrogenase active site for electrocatalytic hydrogen evolution
- Ladda ner fulltext (pdf) av Synthetic styrene-based bioinspired model of the [FeFe]-hydrogenase active site for electrocatalytic hydrogen evolution
Ingår i Journal of Biological Inorganic Chemistry, s. 345-355, 2022
- DOI för Stability of the H-cluster under whole-cell conditions—formation of an Htrans-like state and its reactivity towards oxygen
- Ladda ner fulltext (pdf) av Stability of the H-cluster under whole-cell conditions—formation of an Htrans-like state and its reactivity towards oxygen
Ingår i ACS Sustainable Chemistry and Engineering, s. 10760-10767, 2022
- DOI för Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
- Ladda ner fulltext (pdf) av Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
Ingår i Chemical Science, s. 11058-11064, 2022
- DOI för Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
- Ladda ner fulltext (pdf) av Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
Ingår i Journal of the American Chemical Society, s. 13600-13611, 2022
- DOI för Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
- Ladda ner fulltext (pdf) av Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
Ingår i Dalton Transactions, s. 4634-4643, 2022
- DOI för Lewis acid protection turns cyanide containing [FeFe]-hydrogenase mimics into proton reduction catalysts
- Ladda ner fulltext (pdf) av Lewis acid protection turns cyanide containing [FeFe]-hydrogenase mimics into proton reduction catalysts
Ingår i Chemical Communications, s. 7184-7187, 2022
- DOI för Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
- Ladda ner fulltext (pdf) av Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
Ingår i Chemistry - A European Journal, 2022
- DOI för Non‐Covalent Integration of a [FeFe]‐Hydrogenase Mimic to Multiwalled Carbon Nanotubes for Electrocatalytic Hydrogen Evolution
- Ladda ner fulltext (pdf) av Non‐Covalent Integration of a [FeFe]‐Hydrogenase Mimic to Multiwalled Carbon Nanotubes for Electrocatalytic Hydrogen Evolution
Reversible or Irreversible Catalysis of H+/H2 Conversion by FeFe Hydrogenases
Ingår i Journal of the American Chemical Society, s. 20320-20325, 2021
Ingår i Physiologia Plantarum, s. 555-567, 2021
- DOI för Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
- Ladda ner fulltext (pdf) av Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
Semi-synthetic hydrogenases—in vitro and in vivo applications
Ingår i Current Opinion in Green and Sustainable Chemistry, 2021
- DOI för Semi-synthetic hydrogenases—in vitro and in vivo applications
- Ladda ner fulltext (pdf) av Semi-synthetic hydrogenases—in vitro and in vivo applications
Ingår i Cell Reports Physical Science, 2021
- DOI för Semisynthetic [FeFe]-hydrogenase with stable expression and H2 production capacity in a photosynthetic microbe
- Ladda ner fulltext (pdf) av Semisynthetic [FeFe]-hydrogenase with stable expression and H2 production capacity in a photosynthetic microbe
Ingår i Journal of Biological Inorganic Chemistry, s. 571-582, 2020
- DOI för The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron
- Ladda ner fulltext (pdf) av The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron
Ingår i ACS Catalysis, s. 9943-9952, 2020
- DOI för Carbon Dots and [FeFe] Hydrogenase Biohybrid Assemblies for Efficient Light-Driven Hydrogen Evolution
- Ladda ner fulltext (pdf) av Carbon Dots and [FeFe] Hydrogenase Biohybrid Assemblies for Efficient Light-Driven Hydrogen Evolution
Ingår i Chemical Science, s. 12789-12801, 2020
- DOI för Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
- Ladda ner fulltext (pdf) av Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
Current State of [FeFe]-Hydrogenase Research: Biodiversity and Spectroscopic Investigations
Ingår i ACS Catalysis, s. 7069-7086, 2020
Ingår i Chemical Science, s. 4608-4617, 2020
- DOI för Spectroscopic investigations under whole-cell conditions provide new insight into the metal hydride chemistry of [FeFe]-hydrogenase
- Ladda ner fulltext (pdf) av Spectroscopic investigations under whole-cell conditions provide new insight into the metal hydride chemistry of [FeFe]-hydrogenase
The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions
Ingår i Journal of Biological Chemistry, s. 11891-11901, 2020
- DOI för The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions
- Ladda ner fulltext (pdf) av The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions
Ingår i Journal of Biological Inorganic Chemistry, s. 777-788, 2020
- DOI för [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
- Ladda ner fulltext (pdf) av [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
Ingår i Dalton Transactions, s. 858-865, 2020
- DOI för The reactivity of molecular oxygen and reactive oxygen species with [FeFe] hydrogenase biomimetics: reversibility and the role of the second coordination sphere
- Ladda ner fulltext (pdf) av The reactivity of molecular oxygen and reactive oxygen species with [FeFe] hydrogenase biomimetics: reversibility and the role of the second coordination sphere
Ingår i Chemical Science, s. 5582-5588, 2019
- DOI för Metal vs. ligand protonation and the alleged proton-shuttling role of the azadithiolate ligand in catalytic H-2 formation with FeFe hydrogenase model complexes
- Ladda ner fulltext (pdf) av Metal vs. ligand protonation and the alleged proton-shuttling role of the azadithiolate ligand in catalytic H-2 formation with FeFe hydrogenase model complexes
Ingår i Journal of Biological Inorganic Chemistry, s. 841-848, 2019
- DOI för Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase
- Ladda ner fulltext (pdf) av Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase
Synthesis of a miniaturized [FeFe] hydrogenase model system
Ingår i Dalton Transactions, s. 2280-2284, 2019
- DOI för Synthesis of a miniaturized [FeFe] hydrogenase model system
- Ladda ner fulltext (pdf) av Synthesis of a miniaturized [FeFe] hydrogenase model system
Ingår i Journal of Biological Inorganic Chemistry, s. 849-861, 2019
- DOI för Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access
- Ladda ner fulltext (pdf) av Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access
Discovery of novel [FeFe]-hydrogenases for biocatalytic H-2-production
Ingår i Chemical Science, s. 9941-9948, 2019
- DOI för Discovery of novel [FeFe]-hydrogenases for biocatalytic H-2-production
- Ladda ner fulltext (pdf) av Discovery of novel [FeFe]-hydrogenases for biocatalytic H-2-production
Monitoring H-cluster assembly using a semi-synthetic HydF protein
Ingår i Dalton Transactions, s. 5978-5986, 2019
Ingår i Journal of Biological Inorganic Chemistry, s. 863-877, 2019
- DOI för Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading
- Ladda ner fulltext (pdf) av Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading
Ingår i Faraday discussions, s. 162-174, 2019
- DOI för Photoinduced hole transfer from tris(bipyridine)ruthenium dye to a high-valent iron-based water oxidation catalyst
- Ladda ner fulltext (pdf) av Photoinduced hole transfer from tris(bipyridine)ruthenium dye to a high-valent iron-based water oxidation catalyst
Efficient visible light-driven water oxidation catalysed by an iron(IV) clathrochelate complex
Ingår i Chemical Communications, s. 3335-3338, 2019
- DOI för Efficient visible light-driven water oxidation catalysed by an iron(IV) clathrochelate complex
- Ladda ner fulltext (pdf) av Efficient visible light-driven water oxidation catalysed by an iron(IV) clathrochelate complex
Ingår i Sustainable Energy & Fuels, s. 724-750, 2018
- DOI för From protein engineering to artificial enzymes - biological and biomimetic approaches towards sustainable hydrogen production
- Ladda ner fulltext (pdf) av From protein engineering to artificial enzymes - biological and biomimetic approaches towards sustainable hydrogen production
Ingår i eLIFE, 2018
- DOI för Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit
- Ladda ner fulltext (pdf) av Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit
Ingår i Journal of Biological Chemistry, s. 15889-15900, 2018
- DOI för A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant
- Ladda ner fulltext (pdf) av A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant
InVivo EPR Characterization of Semi-Synthetic [FeFe] Hydrogenases
Ingår i Angewandte Chemie International Edition, s. 2596-2599, 2018
Ingår i Inorganic Chemistry, s. 10424-10430, 2018
Hydrogen evolution by a photoelectrochemical cell based on a Cu2O-ZnO-[FeFe] hydrogenase electrode
Ingår i Journal of Photochemistry and Photobiology A, s. 27-33, 2018
- DOI för Hydrogen evolution by a photoelectrochemical cell based on a Cu2O-ZnO-[FeFe] hydrogenase electrode
- Ladda ner fulltext (pdf) av Hydrogen evolution by a photoelectrochemical cell based on a Cu2O-ZnO-[FeFe] hydrogenase electrode
Generation of a functional, semisynthetic [FeFe]-hydrogenase in a photosynthetic microorganism
Ingår i Energy & Environmental Science, s. 3163-3167, 2018
- DOI för Generation of a functional, semisynthetic [FeFe]-hydrogenase in a photosynthetic microorganism
- Ladda ner fulltext (pdf) av Generation of a functional, semisynthetic [FeFe]-hydrogenase in a photosynthetic microorganism
In vivo activation of an [FeFe] hydrogenase using synthetic cofactors
Ingår i Energy & Environmental Science, s. 1563-1567, 2017
- DOI för In vivo activation of an [FeFe] hydrogenase using synthetic cofactors
- Ladda ner fulltext (pdf) av In vivo activation of an [FeFe] hydrogenase using synthetic cofactors
Ingår i Dalton Transactions, s. 19242-19248, 2016
- DOI för Characterization of a monocyanide model of FeFe hydrogenases - highlighting the importance of the bridgehead nitrogen for catalysis
- Ladda ner fulltext (pdf) av Characterization of a monocyanide model of FeFe hydrogenases - highlighting the importance of the bridgehead nitrogen for catalysis
Ingår i Biochemistry, s. 4197-4211, 2016
From Enzyme Maturation to Synthetic Chemistry: The Case of Hydrogenases
Ingår i Accounts of Chemical Research, s. 2380-2387, 2015
The Origin and Evolution of Ribonucleotide Reduction
Ingår i Life, s. 604-636, 2015
A Systematic Comparative Study of Hydrogen-Evolving Molecular Catalysts in Aqueous Solutions
Ingår i ChemSusChem, s. 3632-3638, 2015