Våra aktuella publiceringar

Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Kopsida, Maria; Clavero, Ada Lerma; Khaled, Jaafar; Balgoma, David et al.

Ingår i Molecular Metabolism, 2024

• DOI för Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
• Ladda ner fulltext (pdf) av Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Metabolite Profiling of Drugs using Mass Spectrometry: Identification of analytical targets for doping control and improvements of the metabolite search process

Nilsson Broberg, Malin

2024

• Ladda ner fulltext (pdf) av Metabolite Profiling of Drugs using Mass Spectrometry: Identification of analytical targets for doping control and improvements of the metabolite search process

A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of chromatography. B, 2023

• DOI för A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
• Ladda ner fulltext (pdf) av A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots

Wiesner, Rebecca; Zagst, Holger; Lan, Wenkui; Bigelow, Stewart et al.

Ingår i Electrophoresis, s. 1247-1257, 2023

• DOI för An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots
• Ladda ner fulltext (pdf) av An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots

Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.

Carlsson, Henrik; Sreenivasan, Akshai P.; Erngren, Ida; Larsson, Anders et al.

Ingår i Environmental Science, s. 1116-1130, 2023

• DOI för Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.
• Ladda ner fulltext (pdf) av Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.

DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob et al.

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, 2023

• DOI för DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
• Ladda ner fulltext (pdf) av DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Enantiomeric Separation of Triacylglycerols from Mouse Liver Tissue using CSP-LC-MS/MS

Landström, Sofia

2023

Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI för Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
• Ladda ner fulltext (pdf) av Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials

Palo-Nieto, Carlos; Blasi-Romero, Anna; Sandström, Corine; Balgoma, David et al.

Ingår i Materials Advances, s. 1555-1565, 2023

• DOI för Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials
• Ladda ner fulltext (pdf) av Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials

Identification and Structural Elucidation of Cannabinoid Metabolites in Horse Urine Using UHPLC-HRMS

Morén, Agnes

2023

• Ladda ner fulltext (pdf) av Identification and Structural Elucidation of Cannabinoid Metabolites in Horse Urine Using UHPLC-HRMS

Investigation of degradation of toxic substances in fungal cultures by mass spectrometric techniques

Stenholm, Åke

2023

• Ladda ner fulltext (pdf) av Investigation of degradation of toxic substances in fungal cultures by mass spectrometric techniques

Optimization of a Microsome Incubation Method using Design of Experiment and Investigation of Metabolites Derived from GLPG0492 and LY2452473: For Application in Doping Control

Tillgren Ohlsson, Rebecca

2023

• Ladda ner fulltext (pdf) av Optimization of a Microsome Incubation Method using Design of Experiment and Investigation of Metabolites Derived from GLPG0492 and LY2452473: For Application in Doping Control

Plasma levels of arginines at term pregnancy in relation to mode of onset of labor and mode of childbirth

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Ubhayasekera, Kumari et al.

Ingår i American Journal of Reproductive Immunology, 2023

• DOI för Plasma levels of arginines at term pregnancy in relation to mode of onset of labor and mode of childbirth
• Ladda ner fulltext (pdf) av Plasma levels of arginines at term pregnancy in relation to mode of onset of labor and mode of childbirth

Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring

van der Burg, Debbie; Josefsson, Leila; Emmer, Åsa; Sänger–van de Griend, Cari E.

Ingår i TrAC. Trends in analytical chemistry, 2023

• DOI för Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring
• Ladda ner fulltext (pdf) av Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring

Screening of HETP test conditions and resin storage solutions for HIC

Ronnerfors, Lise-Lotte

2023

• Ladda ner fulltext (pdf) av Screening of HETP test conditions and resin storage solutions for HIC

Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications-Updated and completely revised edition

Krebs, Finja; Zagst, Holger; Stein, Matthias; Ratih, Ratih et al.

Ingår i Electrophoresis, s. 1279-1341, 2023

• DOI för Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications-Updated and completely revised edition
• Ladda ner fulltext (pdf) av Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications-Updated and completely revised edition

Trials and tribulations of statistical significance in biochemistry and omics

Montero, Olimpio; Hedeland, Mikael; Balgoma, David

Ingår i TIBS -Trends in Biochemical Sciences. Regular ed., s. 503-512, 2023

• DOI för Trials and tribulations of statistical significance in biochemistry and omics
• Ladda ner fulltext (pdf) av Trials and tribulations of statistical significance in biochemistry and omics

Ammonia Concentration in the Eluent Influences Fragmentation Pattern of Triacylglycerols in Mass Spectrometry Analysis

Velasco, Marta; Balgoma, David; Montero, Olimpio

Ingår i Metabolites, 2022

• DOI för Ammonia Concentration in the Eluent Influences Fragmentation Pattern of Triacylglycerols in Mass Spectrometry Analysis
• Ladda ner fulltext (pdf) av Ammonia Concentration in the Eluent Influences Fragmentation Pattern of Triacylglycerols in Mass Spectrometry Analysis

Analytical Quality by Design Method Development for Vaccine Characterization

Geurink, Lars

2022

• Ladda ner fulltext (pdf) av Analytical Quality by Design Method Development for Vaccine Characterization

Comprehensive Peak Characterization (CPC) in Untargeted LC-MS Analysis

Pirttilä, Kristian; Balgoma, David; Rainer, Johannes; Pettersson, Curt et al.

Ingår i Metabolites, 2022

• DOI för Comprehensive Peak Characterization (CPC) in Untargeted LC-MS Analysis
• Ladda ner fulltext (pdf) av Comprehensive Peak Characterization (CPC) in Untargeted LC-MS Analysis

Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Ferrari, Desiree; Lundgren, Sandra; Holmberg, Johanna; Edner, Anna et al.

Ingår i Theriogenology, s. 59-68, 2022

• DOI för Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Developing reactive oxygen species-sensitive cellulose nanofibers for chronic wound care

Palo Nieto, Carlos; Blasi Romero, Anna; Balgoma, David; Hedeland, Mikael et al.

2022

Development and Validation of a Quantitative UHPLC-MS-MS Method for the Determination of Alpha-Chloralose in Feline Blood and Application on Blood Samples Collected from Cats with Symptoms of Alpha-Chloralose Poisoning

Windahl, Ulrika; Lundgren, Sandra; Sprycha, Margareta; Tegner, Cecilia et al.

Ingår i Journal of Analytical Toxicology, s. 651-657, 2022

• DOI för Development and Validation of a Quantitative UHPLC-MS-MS Method for the Determination of Alpha-Chloralose in Feline Blood and Application on Blood Samples Collected from Cats with Symptoms of Alpha-Chloralose Poisoning
• Ladda ner fulltext (pdf) av Development and Validation of a Quantitative UHPLC-MS-MS Method for the Determination of Alpha-Chloralose in Feline Blood and Application on Blood Samples Collected from Cats with Symptoms of Alpha-Chloralose Poisoning

Development of analytical methods for the determination of the small molecule component of complex biological systems

Pirttilä, Kristian

2022

• Ladda ner fulltext (pdf) av Development of analytical methods for the determination of the small molecule component of complex biological systems

Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species

Stenholm, Åke; Hedeland, Mikael; Pettersson, Curt

Ingår i BMC Biotechnology, 2022

• DOI för Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species
• Ladda ner fulltext (pdf) av Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species

Method development for mono- and disaccharides monitoring in cell culture medium by capillary and microchip electrophoresis

van der Burg, Debbie; Josefsson, Leila; Mikkonen, Saara; Chotteau, Veronique et al.

Ingår i Electrophoresis, s. 922-929, 2022

• DOI för Method development for mono- and disaccharides monitoring in cell culture medium by capillary and microchip electrophoresis
• Ladda ner fulltext (pdf) av Method development for mono- and disaccharides monitoring in cell culture medium by capillary and microchip electrophoresis

Neomycin removal using the white rot fungus Trametes versicolor

Stenholm, Åke; Hedeland, Mikael; Pettersson, Curt

Ingår i Journal of Environmental Science and Health. Part A, s. 436-447, 2022

• DOI för Neomycin removal using the white rot fungus Trametes versicolor
• Ladda ner fulltext (pdf) av Neomycin removal using the white rot fungus Trametes versicolor

Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

Steffen, Karin; Indraningrat, Anak Agung Gede; Erngren, Ida; Haglöf, Jakob et al.

Ingår i Scientific Reports, 2022

• DOI för Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
• Ladda ner fulltext (pdf) av Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

On the introduction of reactive oxygen species-sensitive linkers onto cellulose nanofibrils: Towards advanced wound healing solutions.

Palo-Nieto, Carlos; Blasi Romero, Anna; Balgoma, David; Strömme, Maria et al.

2022

Oogenesis and lipid metabolism in the deep-sea sponge Phakellia ventilabrum (Linnaeus, 1767)

Koutsouveli, Vasiliki; Balgoma, David; Checa, Antonio; Hedeland, Mikael et al.

Ingår i Scientific Reports, 2022

• DOI för Oogenesis and lipid metabolism in the deep-sea sponge Phakellia ventilabrum (Linnaeus, 1767)
• Ladda ner fulltext (pdf) av Oogenesis and lipid metabolism in the deep-sea sponge Phakellia ventilabrum (Linnaeus, 1767)

Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding

Balgoma, David; Kullenberg, Fredrik; Peters, Karsten; Dahlgren, David et al.

Ingår i Metabolites, 2022

• DOI för Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
• Ladda ner fulltext (pdf) av Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding

Plasma atropine concentrations associated with decreased intestinal motility in horses

Ekstrand, Carl; Michanek, Peter; Gehring, Ronette; Sundell, Anna et al.

Ingår i Frontiers in Veterinary Science, 2022

• DOI för Plasma atropine concentrations associated with decreased intestinal motility in horses
• Ladda ner fulltext (pdf) av Plasma atropine concentrations associated with decreased intestinal motility in horses

Protein mapping of peanut extract with capillary electrophoresis

Villemet, Loic; Cuchet, Aurelien; Desvignes, Christophe; Sänger van de Griend, Catharina

Ingår i Electrophoresis, s. 1027-1034, 2022

• DOI för Protein mapping of peanut extract with capillary electrophoresis
• Ladda ner fulltext (pdf) av Protein mapping of peanut extract with capillary electrophoresis

Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

Sennefelt Nyman, Sofi; Ahlström, Håkan; Dimopoulou, Angeliki; Dahlgren, David et al.

Ingår i BMJ Open, 2022

• DOI för Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
• Ladda ner fulltext (pdf) av Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

The optimization of a manual dissolution method and its equivalence to automated dissolution

Cicek, Diana

2022

• Ladda ner fulltext (pdf) av The optimization of a manual dissolution method and its equivalence to automated dissolution

A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Nylund, Patrick; Atienza Párraga, Alba; Haglöf, Jakob; De Bruyne, Elke et al.

Ingår i Cell Death and Disease, 2021

• DOI för A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
• Ladda ner fulltext (pdf) av A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

A high-throughput method for screening of protein binding behavior of multimodal anionic exchange ligands

Avedis, Ani

2021

• Ladda ner fulltext (pdf) av A high-throughput method for screening of protein binding behavior of multimodal anionic exchange ligands

Analytical method development in liquid chromatography- mass spectrometry based metabolomics

Erngren, Ida

2021

• Ladda ner fulltext (pdf) av Analytical method development in liquid chromatography- mass spectrometry based metabolomics

Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death

Balgoma, David; Kullenberg, Fredrik; Calitz, Carlemi; Kopsida, Maria et al.

Ingår i Cells, 2021

• DOI för Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
• Ladda ner fulltext (pdf) av Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death

Automated Sequential Analysis of Hydrophilic and Lipophilic Fractions of Biological Samples: Increasing Single-Injection Chemical Coverage in Untargeted Metabolomics

Pirttilä, Kristian; Laurell, Göran; Pettersson, Curt; Hedeland, Mikael

Ingår i Metabolites, 2021

• DOI för Automated Sequential Analysis of Hydrophilic and Lipophilic Fractions of Biological Samples: Increasing Single-Injection Chemical Coverage in Untargeted Metabolomics
• Ladda ner fulltext (pdf) av Automated Sequential Analysis of Hydrophilic and Lipophilic Fractions of Biological Samples: Increasing Single-Injection Chemical Coverage in Untargeted Metabolomics

Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study

Akhter, Tansim; Wikström, Gerhard; Larsson, Marita; Bondesson, Ulf et al.

Ingår i European Journal of Obstetrics, Gynecology, and Reproductive Biology, s. 288-293, 2021

• DOI för Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study
• Ladda ner fulltext (pdf) av Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study

Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats

Dahlgren, David; Olander, Tobias; Sjöblom, Markus; Hedeland, Mikael et al.

Ingår i Acta Pharmaceutica Sinica B, s. 1667-1675, 2021

• DOI för Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
• Ladda ner fulltext (pdf) av Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats

Etherglycerophospholipids and ferroptosis: structure, regulation, and location

Balgoma, David; Hedeland, Mikael

Ingår i Trends in endocrinology and metabolism, s. 960-962, 2021

• DOI för Etherglycerophospholipids and ferroptosis: structure, regulation, and location
• Ladda ner fulltext (pdf) av Etherglycerophospholipids and ferroptosis: structure, regulation, and location

Four-step approach to efficiently develop capillary gel electrophoresis methods for viral vaccine protein analysis

Geurink, Lars; van Tricht, Ewoud; Dudink, Justin; Pajic, Bojana et al.

Ingår i Electrophoresis, s. 10-18, 2021

• DOI för Four-step approach to efficiently develop capillary gel electrophoresis methods for viral vaccine protein analysis

Improved sensitivity in hydrophilic interaction liquid chromatography-electrospray-mass spectrometry after removal of sodium and potassium ions from biological samples

Erngren, Ida; Nestor, Marika; Pettersson, Curt; Hedeland, Mikael

Ingår i Metabolites, 2021

• DOI för Improved sensitivity in hydrophilic interaction liquid chromatography-electrospray-mass spectrometry after removal of sodium and potassium ions from biological samples
• Ladda ner fulltext (pdf) av Improved sensitivity in hydrophilic interaction liquid chromatography-electrospray-mass spectrometry after removal of sodium and potassium ions from biological samples

In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma

Kullenberg, Fredrik; Degerstedt, Oliver; Calitz, Carlemi; Pavlovic, Natasa et al.

Ingår i Cells, 2021

• DOI för In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
• Ladda ner fulltext (pdf) av In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma

Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Metabolites, 2021

• DOI för Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control
• Ladda ner fulltext (pdf) av Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks

Tevell Åberg, Annica; Karlsson, Ida; Hedeland, Mikael

Ingår i Analytical and Bioanalytical Chemistry, s. 345-354, 2021

• DOI för Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks
• Ladda ner fulltext (pdf) av Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks

Prednisolone in Dogs: Plasma Exposure and White Blood Cell Response

Ekstrand, Carl; Pettersson, Helena; Gehring, Ronette; Hedeland, Mikael et al.

Ingår i Frontiers in Veterinary Science, 2021

• DOI för Prednisolone in Dogs: Plasma Exposure and White Blood Cell Response
• Ladda ner fulltext (pdf) av Prednisolone in Dogs: Plasma Exposure and White Blood Cell Response

Quantification of circulating CD19 CAR-T cells in peripheral blood for implementation in routine diagnostics

Sjölund, Hanna

2021

• Ladda ner fulltext (pdf) av Quantification of circulating CD19 CAR-T cells in peripheral blood for implementation in routine diagnostics