Våra aktuella publiceringar
Här tar du del av våra publicerade artiklar inom Theranostics. Välkommen att kontakta oss för ytterligare information om våra resultat.
Ingår i Molecular Pharmaceutics, s. 1919-1932, 2024
Ingår i EJNMMI Radiopharmacy and Chemistry, 2024
- DOI för Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
- Ladda ner fulltext (pdf) av Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
2024
Ingår i Pharmaceutics, 2024
- DOI för GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
- Ladda ner fulltext (pdf) av GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
Ingår i Journal of Controlled Release, s. 468-478, 2024
- DOI för Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
- Ladda ner fulltext (pdf) av Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
Ingår i International Journal of Molecular Sciences, 2024
- DOI för Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
- Ladda ner fulltext (pdf) av Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
Ingår i International Journal of Molecular Sciences, 2024
- DOI för Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
- Ladda ner fulltext (pdf) av Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
Ingår i EJNMMI Radiopharmacy and Chemistry, 2024
- DOI för Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology
- Ladda ner fulltext (pdf) av Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology
Ingår i ACS Pharmacology & Translational Science, s. 1457-1473, 2024
Ingår i ACS Omega, s. 18608-18616, 2024
- DOI för Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
- Ladda ner fulltext (pdf) av Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
Ingår i Frontiers in Oncology, 2023
- DOI för 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
- Ladda ner fulltext (pdf) av 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
Ingår i American Journal of Nuclear Medicine and Molecular Imaging, s. 107-+, 2023
Comparison of HER2-targeted affibody conjugates loaded with auristatin-and maytansine-derived drugs
Ingår i Journal of Controlled Release, s. 515-527, 2023
Ingår i Journal of Controlled Release, s. 185-195, 2023
Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs
2023
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
- Ladda ner fulltext (pdf) av Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
Ingår i Cancers, 2023
- DOI för Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
- Ladda ner fulltext (pdf) av Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
Ingår i Cancers, 2023
- DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
- Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Preclinical Evaluation of a Novel High-Affinity Radioligand [99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
- Ladda ner fulltext (pdf) av Preclinical Evaluation of a Novel High-Affinity Radioligand [99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
Preclinical evaluation of novel therapeutical GRPR-targeting antagonists labeled with 111In
2023
Ingår i Cancers, 2023
- DOI för Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
- Ladda ner fulltext (pdf) av Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
- Ladda ner fulltext (pdf) av Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
Ingår i Diagnostics, 2023
- DOI för The GRPR Antagonist [99mTc]Tc-maSSS-PEG2-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
- Ladda ner fulltext (pdf) av The GRPR Antagonist [99mTc]Tc-maSSS-PEG2-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
Ingår i Oncology Letters, 2023
- DOI för Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125
- Ladda ner fulltext (pdf) av Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125
Ingår i Pharmaceutics, 2022
- DOI för Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
- Ladda ner fulltext (pdf) av Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
Ingår i Pharmaceutics, 2022
- DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
- Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
Ingår i International Journal of Molecular Sciences, 2022
- DOI för Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
- Ladda ner fulltext (pdf) av Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Ingår i Pharmaceutics, 2022
- DOI för Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2
- Ladda ner fulltext (pdf) av Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2
Ingår i Pharmaceutics, 2022
- DOI för Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule 188Re-ZHER2:41071
- Ladda ner fulltext (pdf) av Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule 188Re-ZHER2:41071
In vitro characterization of affibody molecules intended for therapy of EGFR-expressing cancer
2022
PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Ingår i EJNMMI Research, 2022
- DOI för PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
- Ladda ner fulltext (pdf) av PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Ingår i Journal of Nuclear Medicine, s. 528-535, 2022
Ingår i Pharmaceutics, 2022
- DOI för Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
- Ladda ner fulltext (pdf) av Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
Ingår i Biomedicines, 2022
- DOI för Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
- Ladda ner fulltext (pdf) av Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
Ingår i Biomedicines, 2022
- DOI för The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
- Ladda ner fulltext (pdf) av The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
A method of drug delivery to tumors based on rapidly biodegradable drug-loaded containers
Ingår i APPLIED MATERIALS TODAY, 2021
Ingår i Pharmaceutics, 2021
- DOI för Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution
- Ladda ner fulltext (pdf) av Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution
Ingår i Pharmaceutics, 2021
- DOI för Comparative Preclinical Evaluation of HER2-Targeting ABD-Fused Affibody® Molecules 177Lu-ABY-271 and 177Lu-ABY-027: Impact of DOTA Position on ABD Domain
- Ladda ner fulltext (pdf) av Comparative Preclinical Evaluation of HER2-Targeting ABD-Fused Affibody® Molecules 177Lu-ABY-271 and 177Lu-ABY-027: Impact of DOTA Position on ABD Domain
Ingår i Cancers, 2021
- DOI för Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model
- Ladda ner fulltext (pdf) av Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model
Ingår i Diabetes, s. 842-853, 2021
Ingår i Scientific Reports, 2021
- DOI för Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
- Ladda ner fulltext (pdf) av Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
Ingår i Cancers, s. 4791-4791, 2021
- DOI för HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers
- Ladda ner fulltext (pdf) av HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers
Ingår i Cancers, 2021
- DOI för Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model
- Ladda ner fulltext (pdf) av Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model
Improved Radiolytic Stability of a 68Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
Ingår i Pharmaceuticals, 2021
- DOI för Improved Radiolytic Stability of a 68Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
- Ladda ner fulltext (pdf) av Improved Radiolytic Stability of a 68Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
Ingår i Cancers, 2021
- DOI för Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1
- Ladda ner fulltext (pdf) av Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1
PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology
Ingår i International Journal of Molecular Sciences, 2021
- DOI för PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology
- Ladda ner fulltext (pdf) av PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology
Ingår i Journal of Nuclear Medicine, s. 493-499, 2021
Ingår i Bûlleten' sibirskoj mediciny, s. 23-30, 2021
- DOI för Possibilities of radionuclide diagnostics of Her2-positive breast cancer using technetium-99m-labeled target molecules: the first experience of clinical use
- Ladda ner fulltext 1 (pdf) av Possibilities of radionuclide diagnostics of Her2-positive breast cancer using technetium-99m-labeled target molecules: the first experience of clinical use
- Ladda ner fulltext 2 (pdf) av Possibilities of radionuclide diagnostics of Her2-positive breast cancer using technetium-99m-labeled target molecules: the first experience of clinical use
Ingår i Pharmaceutics, 2021
- DOI för Preclinical Evaluation of 99mTc-Labeled GRPR Antagonists maSSS/SES-PEG2-RM26 for Imaging of Prostate Cancer
- Ladda ner fulltext (pdf) av Preclinical Evaluation of 99mTc-Labeled GRPR Antagonists maSSS/SES-PEG2-RM26 for Imaging of Prostate Cancer
Ingår i International Journal of Molecular Sciences, 2021
- DOI för Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake
- Ladda ner fulltext (pdf) av Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake