Research at SweDeliver
Research and Activities at Swedeliver National competence center
Work package Parenteral Drug Delivery
In our Work package Parenteral Drug Delivery we develop new formulations and improved delivery systems for subcutaneous drug administration.
Work package Oral Drug Delivery
In this Work package we improve the design of drug delivery systems that fulfil the requirements for absorption from the small intestine and colon.
Work package Pulmonary Drug Delivery
In this work package we focus on using novel excipients to increase the stability and performance of inhalation powders.
Work package Training & Career Development
In this work package we give our junior researchers the strategic competences for future leading positions in Swedish life science.
Our publications
Access the latest scientific publications based on research conducted at our center contributing new knowledge in the challenges facing drug delivery.
Our junior researchers
Meet the many highly talented PhD students and postdocs who are at the center of our ongoing work to shape the future of drug delivery
Research groups
Research projects
- Combined computational modeling at different scales to understand peptide drug and excipient co-localization
- Diffusion, dissolution, and release mechanisms for dosage forms delivering drugs to the colon: Importance of colonic mucus as a barrier to drug absorption
- Drug delivery platform for optimal intestinal absorption of oral antibiotics
- Effects of molecular characteristics of macromolecular drugs and selection of permeation enhancer on oral absorption
- Exploring the impact of the Gastrointestinal Mucus on drug absorption: Characterization and development of novel predictive tools (finished project)
- Influence of intestinal colloidal structures and self-assembly on lipid-based formulations for enhancing peptide drug bioavailability
- Influence of intra- and extracellular free drug concentrations in the human colon on local and systemic drug exposure
- Investigation of oral absorption of macromolecules using in silico techniques
- Investigation of The Interplay Between Permeation Enhancers, Gi Physiology and Macromolecular Drugs to Facilitate Design of Oral Dosage Forms (finished project)
- In vivo dissolution in colon of poorly soluble drug substances
- Local intestinal generation of transient permeability enhancers by digestion of lipid formulations (finished project)
- Mechanistic modeling of peptide drug permeability
- Amphiphilic Drugs in Microgels (Completed project)
- Amphiphilic Properties of Drug Molecules and Their Self-Assembly in Presence of Phospholipids
- Immunogenicity of synthetic long peptides and the role of formulation and structure for efficacy and toxicity (Completed project)
- Improving FRAP data analysis (Completed project)
- Investigation of the relationship between the in vitro properties of different subcutaneously administered peptides and their bioavailability and absorption in vivo
- In Vitro Methods for Enhanced Understanding of Peptide Transport in Subcutaneous Tissue
- Novel in vitro methods to understand transport properties of biologics (Completed project)
- Novel In Vitro Models for Subcutaneous Administration of Drugs: Transport Properties
- Novel In Vitro Models for Subcutaneous Administration of Drugs (Completed project)
- Physiochemical Aspects of Subcutaneous Administration of Drugs (Completed project)
- Physiologically based biopharmaceutics modeling for subcutaneous drug administration
- Self-assembly of therapeutic peptides
- Subcutaneous administration of biotherapeutics: In vitro properties and bioavailability and absorption rate in vivo
- Adhesive mixtures for inhalation powders
- Development of A Novel Pulmonary Controlled Release Drug Delivery System (Completed project)
- Enhanced spray-dried formulations of inhaled drugs
- Investigation of adhesive layer microstructure of adhesive mixtures using Small Angle X-ray Scattering (Completed project)
- Microstructure-Property Relationships of Agglomerates Formed by Dry Granulation
- Particle Dynamics and Multiscale Modelling of Adhesive Mixtures for Inhaled Medicines (Completed project)
- Understanding the compression–decompression cycle for pressure shaping of agglomerates
- Using novel excipients to improve stability and performance of inhalations powders prepared by spray drying
Contact SweDeliver
Center Director
Professor Christel Bergström,
Department of Pharmacy, Uppsala University
Center co-Director
Associate Professor Alexandra Teleki
Department of Pharmacy, Uppsala University
Project Coordinator
Caroline Fronczak Alvebratt
Department of Pharmacy, Uppsala University