Dyrager Group
![Vials containing solutions that fluoresce in blue and yellow against a black background.](/images/200.35817e118f099f83279bb/1713860614835/Dyrager_startsida_1932px.jpg)
Photo: Susanne Doloczki
Targeting hypoxia in cancer therapy and diagnosis
Our group works on the design and synthesis of “brilliant” (fluorescent) compounds as molecular probes for cell imaging applications. We are mainly interested in compounds that can accumulate specifically in hypoxic cancer cells and thus be used as diagnostic tools in the field of oncology. Our research is multidisciplinary and includes organic synthesis, photophysics, enzymatic reactions and cell studies.
Publications
Part of Proceedings of the National Academy of Sciences of the United States of America, 2024
- DOI for Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma
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Access to long-lived room temperature phosphorescence through auration of 2,1,3-benzothiadiazole
Part of Dalton Transactions, p. 5658-5664, 2024
- DOI for Access to long-lived room temperature phosphorescence through auration of 2,1,3-benzothiadiazole
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Tuning the Emission Properties of 2,1,3‐Benzothiadiazoles via Regioselective Substitution
Part of Chemistry - A European Journal, 2024
- DOI for Tuning the Emission Properties of 2,1,3‐Benzothiadiazoles via Regioselective Substitution
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Part of Journal of Organic Chemistry, p. 6138-6148, 2024
- DOI for Derivatization of 2,1,3-Benzothiadiazole via Regioselective C–H Functionalization and Aryne Reactivity
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An Indolin-3-imine Photobase and pH Sensitive Fluorophore
Part of ChemPhotoChem, 2023
Photoinduced ring‐opening and phototoxicity of an indolin‐3‐one derivative
Part of Chemistry - A European Journal, 2023
- DOI for Photoinduced ring‐opening and phototoxicity of an indolin‐3‐one derivative
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Part of RSC Advances, p. 14544-14550, 2022
- DOI for Photophysical characterization and fluorescence cell imaging applications of 4-N-substituted benzothiadiazoles
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Part of ChemPhotoChem, p. 632-643, 2021
- DOI for Photophysical Characteristics of Polarity-Sensitive and Lipid Droplet-Specific Phenylbenzothiadiazoles
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Prevalent Bioimaging Scaffolds: Synthesis, Photophysical Properties and Applications
Part of European Journal of Organic Chemistry, p. 2133-2144, 2021
- DOI for Prevalent Bioimaging Scaffolds: Synthesis, Photophysical Properties and Applications
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Part of RSC Advances, p. 23960-23967, 2021
- DOI for Indolylbenzothiadiazoles as highly tunable fluorophores for imaging lipid droplet accumulation in astrocytes and glioblastoma cells
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Mechanochemical synthesis of (hetero)aryl Au(i) complexes
Part of Green Chemistry, p. 5648-5655, 2020
- DOI for Mechanochemical synthesis of (hetero)aryl Au(i) complexes
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