Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Part of Acta neuropathologica communications, 2024

• DOI for Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
• Download full text (pdf) of Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Engen, Karin; Lundbäck, Thomas; Yadav, Anubha; Puthiyaparambath, Sharathna et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation
• Download full text (pdf) of Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Download full text (pdf) of N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Part of Molecular Medicine Reports, 2024

• DOI for Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
• Download full text (pdf) of Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET

Schlein, Eva; Rokka, Johanna; Odell, Luke R.; Lopes van den Broek, Sara et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2024

• DOI for Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET
• Download full text (pdf) of Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET

The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Zelleroth, Sofia; Stam, Frida; Nylander, Erik; Ellinor, Kjellgren et al.

Part of Hormones and Behavior, 2024

• DOI for The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat
• Download full text (pdf) of The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Gising, Johan; Honarnejad, Saman; Bras, Maaike; Baillie, Gemma L. et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
• Download full text (pdf) of The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika et al.

Part of ACS Omega, p. 18608-18616, 2024

• DOI for Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
• Download full text (pdf) of Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

Abouzayed, Ayman; Seitova, Kamila; Lundmark, Fanny; Bodenko, Vitalina et al.

Part of Frontiers in Oncology, 2023

• DOI for ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
• Download full text (pdf) of ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Part of Pharmaceutics, 2023

• DOI for [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44
• Download full text (pdf) of [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

A Base-Free, Low Temperature Click and Release Reaction for the In Situ Generation of Diazomethane

Schembri, Luke S; Olaniran, Esther; Söderström, Marcus; Skillinghaug, Bobo et al.

Part of Advanced Synthesis and Catalysis, p. 1839-1845, 2023

• DOI for A Base-Free, Low Temperature Click and Release Reaction for the In Situ Generation of Diazomethane
• Download full text (pdf) of A Base-Free, Low Temperature Click and Release Reaction for the In Situ Generation of Diazomethane

Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study

Dubol, Manon; Immenschuh, Jana; Jonasson, My; Takahashi, Kayo et al.

Part of Comprehensive Psychiatry, 2023

• DOI for Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study
• Download full text (pdf) of Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study

Acyl Amidines by Pd-Catalyzed Aminocarbonylation: One-Pot Cyclizations and C-11 Labeling

Rydfjord, Jonas; Roslin, Sara; Roy, Tamal; Abbas, Alaa et al.

Part of Journal of Organic Chemistry, p. 5078-5089, 2023

• DOI for Acyl Amidines by Pd-Catalyzed Aminocarbonylation: One-Pot Cyclizations and C-11 Labeling
• Download full text (pdf) of Acyl Amidines by Pd-Catalyzed Aminocarbonylation: One-Pot Cyclizations and C-11 Labeling

First-in-human evaluation of [¹⁸F]CETO: a novel tracer for adrenocortical tumours

Silins, Isabella; Sundin, Anders; Lubberink, Mark; O'Sullivan, Lleah et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 398-409, 2023

• DOI for First-in-human evaluation of [¹⁸F]CETO: a novel tracer for adrenocortical tumours
• Download full text (pdf) of First-in-human evaluation of [¹⁸F]CETO: a novel tracer for adrenocortical tumours

In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

Antoni, Gunnar; Lubberink, Mark; Sörensen, Jens; Lindström, Elin et al.

Part of Journal of Nuclear Medicine, p. 145-148, 2023

• DOI for In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES
• Download full text (pdf) of In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging

Kaya, Ibrahim; Schembri, Luke S; Nilsson, Anna; Shariatgorji, Reza et al.

Part of Journal of the American Society for Mass Spectrometry, p. 836-846, 2023

• DOI for On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging
• Download full text (pdf) of On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging

Palladium(0)-Catalyzed Spirocyclization and Carbonylation Reactions: Ligands Targeting the Angiotensin II Type 2 Receptor

Lindman, Jens

2023

• Download full text (pdf) of Palladium(0)-Catalyzed Spirocyclization and Carbonylation Reactions: Ligands Targeting the Angiotensin II Type 2 Receptor

PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Part of Journal of Nuclear Medicine, p. 423-429, 2023

• DOI for PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Part of Cancers, 2023

• DOI for Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
• Download full text (pdf) of Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Larkina, Mariia et al.

Part of International Journal of Molecular Sciences, 2023

• DOI for Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
• Download full text (pdf) of Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Synthesis of Substituted Indazole Acetic Acids by N-N Bond Forming Reactions

Odell, Luke R.; Skillinghaug, Bobo; Matt, Christof; Wu, Peng et al.

Part of European Journal of Organic Chemistry, 2023

• DOI for Synthesis of Substituted Indazole Acetic Acids by N-N Bond Forming Reactions
• Download full text (pdf) of Synthesis of Substituted Indazole Acetic Acids by N-N Bond Forming Reactions

The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity

Abouzayed, Ayman; Borin, Jesper; Lundmark, Fanny; Rybina, Anastasiya et al.

Part of Diagnostics, 2023

• DOI for The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
• Download full text (pdf) of The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity

Thioacetalation and Multi-Component Thiomethylative Friedel-Crafts Arylation Using BF₃SMe₂

Söderström, Marcus; Matt, Christof; Odell, Luke R.

Part of ACS Omega, p. 4320-4330, 2023

• DOI for Thioacetalation and Multi-Component Thiomethylative Friedel-Crafts Arylation Using BF₃SMe₂
• Download full text (pdf) of Thioacetalation and Multi-Component Thiomethylative Friedel-Crafts Arylation Using BF₃SMe₂

¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention

Meier, Silvio R.; Sehlin, Dag; Roshanbin, Sahar; Lim Falk, Victoria et al.

Part of Journal of Nuclear Medicine, p. 302-309, 2022

• DOI for ¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention
• Download full text (pdf) of ¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Part of Bioorganic & Medicinal Chemistry, 2022

• DOI for 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands
• Download full text (pdf) of 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Advancements of nature nanocage protein: preparation, identification and multiple applications of ferritins

Li, Han; Xia, Xiaoyu; Tan, Xiaoyi; Zang, Jiachen et al.

Part of Critical reviews in food science and nutrition, p. 7117-7128, 2022

• DOI for Advancements of nature nanocage protein: preparation, identification and multiple applications of ferritins

Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Gopalan, Greeshma; Palo-Nieto, Carlos; Petersen, Nadia N.; Hallberg, Mathias et al.

Part of Bioorganic & Medicinal Chemistry, 2022

• DOI for Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds
• Download full text (pdf) of Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Chronic cerebral blood flow alterations in traumatic brain injury and sports-related concussions

Vedung, Fredrik; Fahlström, Markus; Wall, Anders; Antoni, Gunnar et al.

Part of Brain Injury, p. 948-960, 2022

• DOI for Chronic cerebral blood flow alterations in traumatic brain injury and sports-related concussions
• Download full text (pdf) of Chronic cerebral blood flow alterations in traumatic brain injury and sports-related concussions

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Part of Pharmaceutics, 2022

• DOI for Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
• Download full text (pdf) of Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

Wall, Anders; Roslin, Sara; Borg, Beatrice; McDermott, Simon et al.

Part of Pharmaceuticals, 2022

• DOI for E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations
• Download full text (pdf) of E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

Schlein, Eva; Syvänen, Stina; Rokka, Johanna; Gustavsson, Tobias et al.

Part of Molecular Pharmaceutics, p. 4111-4122, 2022

• DOI for Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging
• Download full text (pdf) of Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Journal of Nuclear Medicine, p. 794-800, 2022

• DOI for Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

P-119 - Efficient cartridge-based synthesis of a novel [18F]tetrazine for large molecule labelling

Rokka, Johanna; Syvaenen, Stina; Odell, Luke R.; Schlein, Eva et al.

Part of Nuclear Medicine and Biology, 2022

• DOI for P-119 - Efficient cartridge-based synthesis of a novel [18F]tetrazine for large molecule labelling

Palladium-Mediated Synthesis of [Carbonyl-11C]acyl Amidines from Aryl Iodides and Aryl Bromides and Their One-Pot Cyclization to 11C-Labeled Oxadiazoles

Rydfjord, Jonas; Al-Bazaz, Silav; Roslin, Sara

Part of Journal of Organic Chemistry, p. 5118-5126, 2022

• DOI for Palladium-Mediated Synthesis of [Carbonyl-11C]acyl Amidines from Aryl Iodides and Aryl Bromides and Their One-Pot Cyclization to 11C-Labeled Oxadiazoles
• Download full text (pdf) of Palladium-Mediated Synthesis of [Carbonyl-11C]acyl Amidines from Aryl Iodides and Aryl Bromides and Their One-Pot Cyclization to 11C-Labeled Oxadiazoles

PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Part of Pharmaceutical research, p. 1481-1496, 2022

• DOI for PET Imaging in Preclinical Anti-Aβ Drug Development
• Download full text (pdf) of PET Imaging in Preclinical Anti-Aβ Drug Development

Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

Wechalekar, Ashutosh; Antoni, Gunnar; Al Azzam, Wasfi; Bergstrom, Mats et al.

Part of BMC Cardiovascular Disorders, 2022

• DOI for Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study
• Download full text (pdf) of Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Part of NATURE CANCER, p. 156, 2022

• DOI for Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
• Download full text (pdf) of Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

Estrada, Sergio; Elgland, Mathias; Selvaraju, Ram Kumar; Mani, Kevin et al.

Part of Nuclear Medicine and Biology, p. 62-71, 2022

• DOI for Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase
• Download full text (pdf) of Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22

Odell, Luke R.; Robertson, Mark J.; Young, Kelly A.; McGeachie, Andrew B. et al.

Part of ChemMedChem, 2022

• DOI for Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22
• Download full text (pdf) of Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22

Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

Roshanbin, Sahar; Julku, Ulrika; Xiong, Mengfei; Eriksson, Jonas et al.

Part of Pharmaceutics, 2022

• DOI for Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody
• Download full text (pdf) of Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

Fridjonsdottir, Elva; Vallianatou, Theodosia; Mantas, Ioannis; Shariatgorji, Reza et al.

Part of ACS Chemical Biology, p. 147-158, 2022

• DOI for Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems
• Download full text (pdf) of Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy

Hjorth, Olof; Frick, Andreas; Gingnell, Malin; Engman, Jonas et al.

Part of Translational Psychiatry, 2022

• DOI for Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy
• Download full text (pdf) of Serotonin and dopamine transporter availability in social anxiety disorder after combined treatment with escitalopram and cognitive-behavioral therapy

Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Lu, Lu; Åkerbladh, Linda; Ahmad, Shabbir; Konda, Vivek et al.

Part of ACS - Infectious Diseases, p. 482-498, 2022

• DOI for Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)
• Download full text (pdf) of Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Tetramic acid based alkaloids from Aspergillus amoenus Roberg strain UP197-antibiotic properties and new pyranterreones

Nord, Christina; Levenfors, Jolanta J.; Bjerketorp, Joakim; Guss, Bengt et al.

Part of Natural Product Research, p. 967-973, 2022

• DOI for Tetramic acid based alkaloids from Aspergillus amoenus Roberg strain UP197-antibiotic properties and new pyranterreones
• Download full text (pdf) of Tetramic acid based alkaloids from Aspergillus amoenus Roberg strain UP197-antibiotic properties and new pyranterreones

The Angiotensin AT₂ Receptor: From a Binding Site to a Novel Therapeutic Target

Steckelings, U. Muscha; Widdop, Robert E.; Sturrock, Edward D.; Lubbe, Lizelle et al.

Part of Pharmacological Reviews, p. 1051-1135, 2022

• DOI for The Angiotensin AT₂ Receptor: From a Binding Site to a Novel Therapeutic Target

¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Nordeman, Patrik; Jayendra, Z. P.; Briard, E.; Li, Su-Chen et al.

Part of European Journal of Pharmaceutical Sciences, 2021

• DOI for ¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

A Chemical Approach Toward the Therapeutic Optimization of Cytotoxic Bioconjugates

Hartmann, Rafael

2021

• Download full text (pdf) of A Chemical Approach Toward the Therapeutic Optimization of Cytotoxic Bioconjugates

A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Rokka, Johanna; Nordeman, Patrik; Bergman, Sara; Eriksson, Jonas

Part of Journal of labelled compounds & radiopharmaceuticals, p. 447-455, 2021

• DOI for A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media
• Download full text (pdf) of A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Base-catalysed F-18-labelling of trifluoromethyl ketones. Application to the synthesis of F-18-labelled neutrophil elastase inhibitors

Meyer, Denise N.; Cortes Gonzalez, Miguel A.; Jiang, Xingguo; Johansson-Holm, Linus et al.

Part of Chemical Communications, p. 8476-8479, 2021

• DOI for Base-catalysed F-18-labelling of trifluoromethyl ketones. Application to the synthesis of F-18-labelled neutrophil elastase inhibitors
• Download full text (pdf) of Base-catalysed F-18-labelling of trifluoromethyl ketones. Application to the synthesis of F-18-labelled neutrophil elastase inhibitors

Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Diabetes, p. 842-853, 2021

• DOI for Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography