Functional Pharmacology and Neuroscience
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Photo: Mikael Wallerstedt
The research group of Functional Pharmacology and Neuroscience conducts pharmacological, toxicological, genetic, and behavioral studies related to drugs, environmental toxins, diseases, behaviors, and environmental changes.
The research group use several experimental models, including humans and animals such as flies and mice. They investigate the side effects of drugs to understand the molecular, cell specific and genetic causes behind their toxic effects. They examine the mechanisms of environmental toxins impact, in connection with several diseases and identify blood biomarkers for diagnosing different conditions. They study various types of behaviors, such as food intake and addiction, and attempt to elucidate the molecular mechanisms. They also map large gene and protein families as well as molecular signaling pathways.
The group has an interdisciplinary environment that promotes career opportunities for doctoral students and postdoctoral fellows. They are a highly productive unit with several high-quality publications and significant citations and the PI is one of the most cited researcher in the world. Their teachers teach on the medical program, the biomedical program, the master's program in biomedicine, and other relevant courses.
Publications
Part of Frontiers in Neuroscience, 2024
- DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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Part of Polymers, 2024
- DOI for Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
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Part of Frontiers in Psychiatry, 2024
- DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
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Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
Part of Diabetes/Metabolism Research Reviews, 2024
- DOI for Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
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Part of Scientific Reports, 2024
- DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
Part of Neuroscience and Biobehavioral Reviews, 2024
- DOI for A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
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Part of BMC Public Health, 2024
- DOI for Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study
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Giardia telomeres and telomerase
Part of Parasitology Research, 2024
- DOI for Giardia telomeres and telomerase
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Part of Journal of medical systems, 2024
2024
Part of Cancer Letters, 2024
- DOI for STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
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The Pattern of GH Action in the Mouse Brain
Part of Endocrinology, 2024
Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
Part of Frontiers in Psychiatry, 2024
- DOI for Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
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The profiles of social anxiety and impulsivity among college students: differences in aggression
Part of Current Psychology, p. 10621-10630, 2024
A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Part of Frontiers in Aging Neuroscience, 2024
- DOI for A deep learning model for brain age prediction using minimally preprocessed T1w images as input
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Idiopathic granulomatous orchitis: A case study
Part of Urology Case Reports, 2024
- DOI for Idiopathic granulomatous orchitis: A case study
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Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024
Part of International Journal of Molecular Sciences, 2023
- DOI for Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
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Part of Clinical Epigenetics, 2023
- DOI for Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
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Part of Age and Ageing, 2023
Investigating mental health disorders in relation to job and living related factors
2023
Part of Neuroendocrinology, p. 64-79, 2023
Part of Reproduction, p. 123-134, 2023
Part of Biomedicines, 2023
- DOI for Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
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Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
Part of Journal of Clinical Medicine, 2023
- DOI for Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
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Ghrelin proteolysis increases in plasma of men, but not women, with obesity
Part of Life Sciences, 2023
Part of Clinica Chimica Acta, 2023
- DOI for Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma
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Part of Frontiers in Psychology, 2023
- DOI for The psychological process of stereotyping: Content, forming, internalizing, mechanisms, effects, and interventions
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Job satisfaction has differential associations with delay discounting and risk-taking
Part of Scientific Reports, 2023
- DOI for Job satisfaction has differential associations with delay discounting and risk-taking
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Part of Hematological Oncology, p. 26-38, 2023
- DOI for DNA damage accumulation and repair defects in FLT3‐ITD acute myeloid leukemia: Implications for clonal evolution and disease progression
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Part of Journal of personality, p. 856-867, 2023
- DOI for Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
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Part of Journal of Applied Toxicology, p. 458-469, 2023
- DOI for Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
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Mind & Well-being: The relationships between personality and health related pathology
2023
Part of Alimentary Pharmacology and Therapeutics, p. 475-485, 2023
Part of Frontiers in Psychology, 2023
- DOI for Regional differences in personalities account for substantial heterogeneity of loneliness change from before to during the COVID-19
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Part of BMC Psychology, 2023
- DOI for Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting
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Part of International Journal of Molecular Sciences, 2023
Validity issues in measures of COVID-19 preventive behaviours
Part of Journal of Global Health, 2023
- DOI for Validity issues in measures of COVID-19 preventive behaviours
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Part of Molecular Autism, 2023
- DOI for Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels
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Part of Psychoneuroendocrinology, 2023
The psycho-metabolic consequences of sleep loss in people
2023
Part of The Lancet Healthy Longevity, 2023
- DOI for Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank
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Part of Cancer Science, p. 2360-2374, 2023
- DOI for Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis
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Part of Molecular Neurobiology, p. 2644-2660, 2023
Part of Journal of Pediatric Hematology/Oncology Nursing, p. 158-169, 2023
- DOI for Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish–German Study
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Part of Basic & Clinical Pharmacology & Toxicology, p. 130-141, 2023
- DOI for The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression
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Perceived stress is related to lower blood pressure in a Swedish cohort
Part of Scandinavian Journal of Public Health, p. 611-618, 2023
- DOI for Perceived stress is related to lower blood pressure in a Swedish cohort
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Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2023
Part of Appetite, 2023
Ghrelin Action in the PVH of Male Mice: Accessibility, Neuronal Targets, and CRH Neurons Activation
Part of Endocrinology, 2023