Funktionell farmakologi och neurovetenskap

Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Ingår i Frontiers in Neuroscience, 2024

• DOI för Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
• Ladda ner fulltext (pdf) av Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi

Ingår i Polymers, 2024

• DOI för Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
• Ladda ner fulltext (pdf) av Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

Mohamed, Mohamed S.; Rukh, Gull; Vadlin, Sofia; Olofsdotter, Susanne et al.

Ingår i Frontiers in Psychiatry, 2024

• DOI för Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
• Ladda ner fulltext (pdf) av Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes

Xu, Xiaoqin; Li, Jiang; Yu, Yuefeng; Tan, Xiao et al.

Ingår i Diabetes/Metabolism Research Reviews, 2024

• DOI för Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
• Ladda ner fulltext (pdf) av Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Ingår i Scientific Reports, 2024

• DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
• Ladda ner fulltext (pdf) av Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)

Brooks, Samantha; Dahl, K.; Dudley-Jones, R.; Schiöth, Helgi

Ingår i Neuroscience and Biobehavioral Reviews, 2024

• DOI för A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
• Ladda ner fulltext (pdf) av A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)

Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study

Mao, Yanhui; Chen, Junpeng; Liu, Xinqi; Dang, Junhua et al.

Ingår i BMC Public Health, 2024

• DOI för Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study
• Ladda ner fulltext (pdf) av Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study

Giardia telomeres and telomerase

Lagunas-Rangel, Francisco Alejandro

Ingår i Parasitology Research, 2024

• DOI för Giardia telomeres and telomerase
• Ladda ner fulltext (pdf) av Giardia telomeres and telomerase

Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Moulin, Thiago C.

Ingår i Journal of medical systems, 2024

• DOI för Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Beating of hammers

Affatato, Oreste

2024

• Ladda ner fulltext (pdf) av Beating of hammers

STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Liu, Jiale; Liu, Chenmian; Ma, Yana; Pan, Xiyu et al.

Ingår i Cancer Letters, 2024

• DOI för STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
• Ladda ner fulltext (pdf) av STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines

Namiot, Eugenia D.; Sokolov, Aleksandr V.; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
• Ladda ner fulltext (pdf) av Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Sokolov, Aleksandr V.; Manu, Diana-Maria; Nordberg, Didi O. T.; Boström, Adrian D. E. et al.

Ingår i Clinical Epigenetics, 2023

• DOI för Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
• Ladda ner fulltext (pdf) av Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Physical frailty, adherence to ideal cardiovascular health and risk of cardiovascular disease: a prospective cohort study

Chen, Liangkai; Li, Xingbang; Lv, Yanling; Tan, Xiao et al.

Ingår i Age and Ageing, 2023

• DOI för Physical frailty, adherence to ideal cardiovascular health and risk of cardiovascular disease: a prospective cohort study

Investigating mental health disorders in relation to job and living related factors

Mohammad, Salahuddin

2023

• Ladda ner fulltext (pdf) av Investigating mental health disorders in relation to job and living related factors

Systemic ghrelin treatment induces rapid, transient and asymmetric changes in the metabolic activity of the mouse brain

De Francesco, Pablo Nicolas; Fernandez, Gimena; Uriarte, Maia; Urrutia, Leandro et al.

Ingår i Neuroendocrinology, s. 64-79, 2023

• DOI för Systemic ghrelin treatment induces rapid, transient and asymmetric changes in the metabolic activity of the mouse brain

Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

Poretti, María Belén; Bianconi, Santiago; Luque, Eugenia; Martini, Ana Carolina et al.

Ingår i Reproduction, s. 123-134, 2023

• DOI för Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

Moulin, Thiago; Stojanovic, Tijana; Rajesh, Rasika P.; Pareek, Tirusha et al.

Ingår i Biomedicines, 2023

• DOI för Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
• Ladda ner fulltext (pdf) av Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic

Mohamed, Mohamed S.; Rukh, Gull; Schiöth, Helgi B.; Vadlin, Sofia et al.

Ingår i Journal of Clinical Medicine, 2023

• DOI för Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
• Ladda ner fulltext (pdf) av Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic

Ghrelin proteolysis increases in plasma of men, but not women, with obesity

Fittipaldi, Antonela S.; Castrogiovanni, Daniel; Lufrano, Daniela; Saenz, Camila et al.

Ingår i Life Sciences, 2023

• DOI för Ghrelin proteolysis increases in plasma of men, but not women, with obesity

Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma

Gui, Xinru; Zhang, Xin; Xin, Yiwei; Liu, Qi et al.

Ingår i Clinica Chimica Acta, 2023

• DOI för Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma
• Ladda ner fulltext (pdf) av Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma

The psychological process of stereotyping: Content, forming, internalizing, mechanisms, effects, and interventions

Zhang, Baoshan; Hu, Yibo; Zhao, Fengqing; Wen, Fangfang et al.

Ingår i Frontiers in Psychology, 2023

• DOI för The psychological process of stereotyping: Content, forming, internalizing, mechanisms, effects, and interventions
• Ladda ner fulltext (pdf) av The psychological process of stereotyping: Content, forming, internalizing, mechanisms, effects, and interventions

Job satisfaction has differential associations with delay discounting and risk-taking

de Ruijter, Markus J. T.; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B.

Ingår i Scientific Reports, 2023

• DOI för Job satisfaction has differential associations with delay discounting and risk-taking
• Ladda ner fulltext (pdf) av Job satisfaction has differential associations with delay discounting and risk-taking

DNA damage accumulation and repair defects in FLT3‐ITD acute myeloid leukemia: Implications for clonal evolution and disease progression

Lagunas-Rangel, Francisco Alejandro

Ingår i Hematological Oncology, s. 26-38, 2023

• DOI för DNA damage accumulation and repair defects in FLT3‐ITD acute myeloid leukemia: Implications for clonal evolution and disease progression
• Ladda ner fulltext (pdf) av DNA damage accumulation and repair defects in FLT3‐ITD acute myeloid leukemia: Implications for clonal evolution and disease progression

Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study

Rukh, Gull; de Ruijter, Markus; Schiöth, Helgi Birgir

Ingår i Journal of personality, s. 856-867, 2023

• DOI för Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
• Ladda ner fulltext (pdf) av Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study

Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells

Lagunas-Rangel, Francisco Alejandro; Liu, Wen; Schiöth, Helgi B.

Ingår i Journal of Applied Toxicology, s. 458-469, 2023

• DOI för Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
• Ladda ner fulltext (pdf) av Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells

Mind & Well-being: The relationships between personality and health related pathology

de Ruijter, Markus J. T.

2023

• Ladda ner fulltext (pdf) av Mind & Well-being: The relationships between personality and health related pathology

Sleep duration and daytime napping in relation to incident inflammatory bowel disease: a prospective cohort study

Yuan, Shuai; Sun, Yuhao; Tan, Xiao; Geng, Jiawei et al.

Ingår i Alimentary Pharmacology and Therapeutics, s. 475-485, 2023

• DOI för Sleep duration and daytime napping in relation to incident inflammatory bowel disease: a prospective cohort study

Regional differences in personalities account for substantial heterogeneity of loneliness change from before to during the COVID-19

Xiao, Shanshan; Dang, Junhua

Ingår i Frontiers in Psychology, 2023

• DOI för Regional differences in personalities account for substantial heterogeneity of loneliness change from before to during the COVID-19
• Ladda ner fulltext (pdf) av Regional differences in personalities account for substantial heterogeneity of loneliness change from before to during the COVID-19

Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting

Ji, Huazhen; Zhao, Xiaoyun; Dang, Junhua

Ingår i BMC Psychology, 2023

• DOI för Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting
• Ladda ner fulltext (pdf) av Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting

The Epigenetics of Migraine

Zobdeh, Farzin; Eremenko, Ivan I.; Akan, Mikail A.; Tarasov, Vadim V. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för The Epigenetics of Migraine
• Ladda ner fulltext (pdf) av The Epigenetics of Migraine

Validity issues in measures of COVID-19 preventive behaviours

Dang, Junhua; Jia, Lile

Ingår i Journal of Global Health, 2023

• DOI för Validity issues in measures of COVID-19 preventive behaviours
• Ladda ner fulltext (pdf) av Validity issues in measures of COVID-19 preventive behaviours

Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Liepinsh, Edgars; Svalbe, Baiba; Stelfa, Gundega; Grinberga, Solveiga et al.

Ingår i Molecular Autism, 2023

• DOI för Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels
• Ladda ner fulltext (pdf) av Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

Barrile, Franco; Cassano, Daniela; Fernandez, Gimena; De Francesco, Pablo N. et al.

Ingår i Psychoneuroendocrinology, 2023

• DOI för Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

The psycho-metabolic consequences of sleep loss in people

van Egmond, Lieve T.

2023

• Ladda ner fulltext (pdf) av The psycho-metabolic consequences of sleep loss in people

Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank

Feng, Hongliang; Yang, Lulu; Ai, Sizhi; Liu, Yue et al.

Ingår i The Lancet Healthy Longevity, 2023

• DOI för Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank
• Ladda ner fulltext (pdf) av Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank

Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis

Xin, Yiwei; Li, Xinyang; Zhang, Mengjiao; Shang, Ziqi et al.

Ingår i Cancer Science, s. 2360-2374, 2023

• DOI för Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis
• Ladda ner fulltext (pdf) av Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis

Chlorpromazine, an Inverse Agonist of D1R-Like, Differentially Targets Voltage-Gated Calcium Channel (Ca_V) Subtypes in mPFC Neurons

McCarthy, Clara Inés; Mustafá, Emilio Román; Cornejo, María Paula; Yaneff, Agustín et al.

Ingår i Molecular Neurobiology, s. 2644-2660, 2023

• DOI för Chlorpromazine, an Inverse Agonist of D1R-Like, Differentially Targets Voltage-Gated Calcium Channel (Ca_V) Subtypes in mPFC Neurons

Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish–German Study

Witt, Stefanie; Quitmann, Julia; Höglund, Anna T; Russ, Sandra et al.

Ingår i Journal of Pediatric Hematology/Oncology Nursing, s. 158-169, 2023

• DOI för Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish–German Study
• Ladda ner fulltext (pdf) av Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish–German Study

The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression

Lax, Cassandra; Wicksell, Elin; Grip, Anastasia; Niemi, Jenni Viivi Linnea et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 130-141, 2023

• DOI för The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression
• Ladda ner fulltext (pdf) av The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression

Perceived stress is related to lower blood pressure in a Swedish cohort

Miguet, Maud; Olivo, Gaia; Ciuculete, Diana-Maria; Elmståhl, Sölve et al.

Ingår i Scandinavian Journal of Public Health, s. 611-618, 2023

• DOI för Perceived stress is related to lower blood pressure in a Swedish cohort
• Ladda ner fulltext (pdf) av Perceived stress is related to lower blood pressure in a Swedish cohort

The effects of statins on cognitive performance are mediated by low-density lipoprotein, C-reactive protein and blood glucose concentrations.

Gentreau, Mélissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura E et al.

Ingår i The journals of gerontology. Series A, Biological sciences and medical sciences, 2023

• DOI för The effects of statins on cognitive performance are mediated by low-density lipoprotein, C-reactive protein and blood glucose concentrations.

The energy content of meals with a similar macronutrient distribution may have a greater impact on appetite sensations than food preferences in adolescents with obesity: A secondary analysis

Moore, Halim; Siroux, Julie; Pereira, Bruno; Miguet, Maud et al.

Ingår i Appetite, 2023

• DOI för The energy content of meals with a similar macronutrient distribution may have a greater impact on appetite sensations than food preferences in adolescents with obesity: A secondary analysis

Ghrelin Action in the PVH of Male Mice: Accessibility, Neuronal Targets, and CRH Neurons Activation

Fernandez, Gimena; De Francesco, Pablo N.; Cornejo, Maria P.; Cabral, Agustina et al.

Ingår i Endocrinology, 2023

• DOI för Ghrelin Action in the PVH of Male Mice: Accessibility, Neuronal Targets, and CRH Neurons Activation

Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study

Gaudio, Santino; Rukh, Gull; Di Ciommo, Vincenzo; Berkins, Samuel et al.

Ingår i NeuroImage, 2023

• DOI för Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
• Ladda ner fulltext (pdf) av Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study

Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Mälarstig, Anders; Grassmann, Felix; Dahl, Leo; Dimitriou, Marios et al.

Ingår i Nature Communications, 2023

• DOI för Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
• Ladda ner fulltext (pdf) av Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Lagunas-Rangel, Francisco Alejandro; Liao, Sifang; Williams, Michael J.; Trukhan, Vladimir et al.

Ingår i Biomedicines, 2023

• DOI för Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
• Ladda ner fulltext (pdf) av Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls.

Lafta, Muataz S; Sokolov, Aleksandr V.; Landtblom, Anne-Marie; Ericson, Hans et al.

Ingår i European Journal of Pain, 2023

• DOI för Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls.

Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner.

Andreoli, María F; Fittipaldi, Antonela S; Castrogiovanni, Daniel; De Francesco, Pablo N et al.

Ingår i European Journal of Nutrition, 2023

• DOI för Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner.

Physical Activity Intensity, Genetic Predisposition, and Risk of Nonalcoholic Fatty Liver Disease: A Prospective Cohort Study

Lv, Yanling; Ding, Ding; Luo, Mengyun; Tan, Xiao et al.

Ingår i Clinical Gastroenterology and Hepatology, 2023

• DOI för Physical Activity Intensity, Genetic Predisposition, and Risk of Nonalcoholic Fatty Liver Disease: A Prospective Cohort Study