Facilities and equipment and Equipment

In vivo laboratory

Mediso 3T nanoPET-MRI

A preclinical small animal scanner for magnetic resonance imaging (MRI) and positron emission tomography (PET). The superconducting 3 Tesla magnet allows MRI with a spatial resolution down to 100 µm and the PET has a resolution of 700 µm. The absolute quantification accuracy is over 97%. (Installed 2016)

Preclinical PET-MRI scanner

Mediso 3T PET-MRI scanner

Mediso 3T nanoPET-MRI

A preclinical small animal scanner for magnetic resonance imaging (MRI) and positron emission tomography (PET). The superconducting 3 Tesla magnet allows MRI with a spatial resolution down to 100 µm and the PET has a resolution of 700 µm. The absolute quantification accuracy is over 97%. (Installed 2016)

Mediso preclinical SPECT-CT scanner

Mediso preclinical SPECT-CT scanner

2D-PET

A preclinical small animal scanner for 2D positron emission tomography (PET). This instrument fulfils the gap between ex vivo biodistributions and our more advanced multimodal imaging systems. Planar mode is a fast method for in vivo screening of various biomolecules. (Installed 2023)

Beta eye

Beta eye

In vitro laboratory

Cryotome

Cryotome to make thin tissue slices from frozen sections. (Installed 2019)

Cryotome

Cryotome

Microscope

NikonCi microscope with LED illumination and digital image capturing. (Installed 2019)

MicroscopeZoom image

Microscopeule

Cell incubators

In the cell laboratory there are two cell incubators.

IncubatorZoom image

Incubator

Typhoon Phosphorimager

GE Typhoon phosphorimager system for high resolution high sensitivity autoradiopgraphy of frozen sections. (Installed 2018)

typhoonZoom image

Typhoon

Gamma counter, Perkin Elmer Wizard2

Suitable for high energy gamma emitters, low activity samples. Ideal for all gamma emitters-broad energy range (up to 2 000 keV) allows studies of various nuclides. Isotope library contains information for 51 radionuclides. (Installed 2015)

Gamma counterZoom image

Gamma counter

Well counter

For organ biodistriution. An in house 5 well design with with high sensitivity and accurate measurment of large series with low radioactivity in biological samples. Used extensively in in vivo biodistribution studies of tracers with short-lived radionuclides. (New software 2019)

Cell harvester

A cell harvester suitable for radioactive work.

Cell harvesterZoom image

Cell harvester

Ligandtracer Yellow

Monitors molecular interactions in real-time on a spinning petri dish with living cells. Model ywllow is suitable for studies with high energy gamma emitters. (Installed 2019)

Ligand tracer yellowZoom image

Ligand tracer yellow

Radiochemistry laboratory

HPLC systems: Chromaster Alpha HPLC and Chromaster Beta

Chromater Alpha: An HPLC-UV-RADIO system for semipreparative purification and analysis.The system runs with OpenLAB software and the pump manage up to 10 mL/min. The UV detector has a remote flow cell placed inside the shielded fume hood. (Installed 2015)

Chromaster Beta: Analytical HPLC-UV-RADIO system. The system runs with Chromaster software. The UV-detector is a diode array dector (DAD) which simultaneously analyze a range of wavelenghts. This system is also equipped with an automated fraction collector. (Installed 2019)

HPLC pump module

HPLC pump module

Ion chambers (dose calibrators)

The radiochemistry laboratory is equipped with two ion chambers and is used to measure radioactivity in radiochemistry optimisation. (Installed 2019)

Ion chamberZoom image

Ion chamber

Gallium-68 generator

The gallium-68 generator is used to produce gallium-68 for radiochemistry work. It can be eluted 2-3 times per day. (Generator renewed anually)

Gallium-68 generatorZoom image

Gallium-68 generator

Automated Synthesis Module

GE FastLab2, an cassette based automated syntheis module for productions of standardised PET and SPECT tracers. (Installed 2020)

GE FastLab2 synthesis moduleZoom image

GE FastLab2 synthesis module

Cyclone Phosphorimager

High resolution filmless autoradiography. Quantitative images for all commonly used radioisotopes. Used for instant thin layer chromatography anaysis (iTLC) in radiochemistry as well as autoradiography of thin tissue slices.

PerkinElmber Cyclone phosphorimagerZoom image

PerkinElmber Cyclone phosphorimager

FOLLOW UPPSALA UNIVERSITY ON

facebook
instagram
twitter
youtube
linkedin