Physically and Chemically Crosslinked Hyaluronic Acid-Based Hydrogels Differentially Promote Axonal Outgrowth from Neural Tissue Cultures

Bajic, Andrej; Andersson, Brittmarie; Ossinger, Alexander; Tavakoli, Shima et al.

Part of Biomimetics, 2024

• DOI for Physically and Chemically Crosslinked Hyaluronic Acid-Based Hydrogels Differentially Promote Axonal Outgrowth from Neural Tissue Cultures
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A quality by design approach to optimise disulfide-linked hyaluronic acid hydrogels

Ranamalla, Saketh Reddy; Tavakoli, Shima; Porfire, Alina Silvia; Tefas, Lucia Ruxandra et al.

Part of Carbohydrate Polymers, 2024

• DOI for A quality by design approach to optimise disulfide-linked hyaluronic acid hydrogels
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Fine-tuning Dynamic Cross-linking for Enhanced 3D Bioprinting of Hyaluronic Acid Hydrogels

Tavakoli, Shima; Krishnan, Nithiyanandan; Mokhtari, Hamidreza; Oommen, Oommen P. et al.

Part of Advanced Functional Materials, 2024

• DOI for Fine-tuning Dynamic Cross-linking for Enhanced 3D Bioprinting of Hyaluronic Acid Hydrogels
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Advances in Intracellular and On-Surface Polymerization in Living Cells: Implications for Nanobiomedicines

Laskar, Partha; Varghese, Oommen P.; Shastri, V. Prasad

Part of Advanced NanoBiomed Research, 2023

• DOI for Advances in Intracellular and On-Surface Polymerization in Living Cells: Implications for Nanobiomedicines
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Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function

Rangasami, Vignesh K.; Asawa, Kenta; Teramura, Yuji; Le Blanc, Katrina et al.

Part of Biomaterials Advances, 2023

• DOI for Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function
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Unveiling extracellular matrix assembly: Insights and approaches through bioorthogonal chemistry

Tavakoli, Shima; Evans, Austin; Oommen, Oommen P.; Creemers, Laura et al.

Part of MATERIALS TODAY BIO, 2023

• DOI for Unveiling extracellular matrix assembly: Insights and approaches through bioorthogonal chemistry
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Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model

Samanta, Sumanta; Le Joncour, Vadim; Wegrzyniak, Olivia; Rangasami, Vignesh K. et al.

Part of Advanced Therapeutics, 2022

• DOI for Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
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Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype

Samanta, Sumanta; Rangasami, Vignesh K.; Sarlus, Heela; Samal, Jay R. K. et al.

Part of Acta Biomaterialia, p. 36-48, 2022

• DOI for Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype
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Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications

Wang, Shujiang; Tavakoli, Shima; Parvathaneni, Rohith Pavan; Nawale, Ganesh N. et al.

Part of Biomaterials Science, p. 6399-6412, 2022

• DOI for Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
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Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures

Kadekar, Sandeep; Barbe, Laurent; Stoddart, Martin; Varghese, Oommen P. et al.

Part of Cellular and Molecular Bioengineering, p. 121-130, 2021

• DOI for Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures
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Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery

Kadekar, Sandeep; Nawale, Ganesh N.; Rangasami, Vignesh K.; Le Joncour, Vadim et al.

Part of Biomaterials Science, p. 3939-3944, 2021

• DOI for Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
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Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate

Samal, Jay R. K.; Rangasami, Vignesh K.; Samanta, Sumanta; Varghese, Oommen P. et al.

Part of Advanced Healthcare Materials, 2021

• DOI for Discrepancies on the Role of Oxygen Gradient and Culture Condition on Mesenchymal Stem Cell Fate
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An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels

Samanta, Sumanta; Rangasami, Vignesh K.; Murugan, N. Arul; Parihar, Vijay Singh et al.

Part of Polymer Chemistry, p. 2987-2991, 2021

• DOI for An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels
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PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications

Carter, Sarah-Sophia; Atif, Abdul Raouf; Kadekar, Sandeep; Lanekoff, Ingela et al.

Part of Organs-on-a-Chip, 2020

• DOI for PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
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Modulating thiol pK_a promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels

Bermejo-Velasco, Daniel; Azémar, Alice; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Biomacromolecules, p. 1412-1420, 2019

• DOI for Modulating thiol pK_a promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels

First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

Bermejo-Velasco, Daniel; Kadekar, Sandeep; Tavares da Costa, Marcus Vinicius; Oommen, Oommen P. et al.

Part of ACS Applied Materials and Interfaces, p. 38232-38239, 2019

• DOI for First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification

Han, Yuanyuan; Qiu, Zhen; Nawale, Ganesh N.; Varghese, Oommen P. et al.

Part of Biosensors & bioelectronics, p. 188-193, 2019

• DOI for MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification

Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection

Kadekar, Sandeep; Nawale, Ganesh N.; Karlsson, Kira; Ålander, Cecilia et al.

Part of Molecular Therapy Nucleic Acids, p. 597-604, 2019

• DOI for Synthetic design of asymmetric miRNA with engineered 3′-overhang to improve strand selection
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A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells

Mittapelli, Lavanya L.; Nawale, Ganesh N.; Gholap, Sachin P.; Varghese, Oommen P. et al.

Part of Sensors and actuators. B, Chemical, 2019

• DOI for A turn-on fluorescent GFP chromophore analog for highly selective and efficient detection of H2S in aqueous and in living cells

4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading

Nawale, Ganesh N.; Bahadorikhalili, Saeed; Sengupta, Pallabi; Kadekar, Sandeep et al.

Part of Chemical Communications, p. 9112-9115, 2019

• DOI for 4 '-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading
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Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy

Paidikondala, Maruthibabu; Kadekar, Sandeep; Varghese, Oommen P.

Part of International Journal of Molecular Sciences, 2019

• DOI for Innovative strategy for 3D transfection of primary human stem cells with BMP-2 expressing plasmid DNA: A clinically translatable strategy for ex vivogene therapy
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Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel

Paidikondala, Maruthibabu; Nawale, Ganesh N.; Varghese, Oommen P.

Part of Biomacromolecules, p. 1317-1324, 2019

• DOI for Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel

An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method

Paidikondala, Maruthibabu; Rangasami, Vignesh Kumar; Nawale, Ganesh N.; Casalini, Tommaso et al.

Part of Angewandte Chemie International Edition, p. 2815-2819, 2019

• DOI for An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method

Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2

Paidikondala, Maruthibabu; Wang, Shujiang; Hilborn, Jöns; Larsson, Sune et al.

Part of ACS Applied Bio Materials, 2019

• DOI for Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2

Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels

Wang, Shujiang; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Polymer Chemistry, p. 4322-4327, 2019

• DOI for Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
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Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH

Bermejo-Velasco, Daniel; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Chemical Communications, p. 12507-12510, 2018

• DOI for Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
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Bi-directional cell-pericellular matrix interactions direct stem cell fate

Ferreira, Silvia A; Motwani, Meghna S; Faull, Peter A; Seymour, Alexis J et al.

Part of Nature Communications, 2018

• DOI for Bi-directional cell-pericellular matrix interactions direct stem cell fate
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Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH

Wang, Shujiang; Nawale, Ganesh N.; Kadekar, Sandeep; Oommen, Oommen P. et al.

Part of Scientific Reports, 2018

• DOI for Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
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Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

Yan, Hongji; Casalini, Tommaso; Hulsart Billström, Gry; Wang, Shujiang et al.

Part of Biomaterials, p. 190-202, 2018

• DOI for Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering

Roshanbinfar, Kaveh; Hilborn, Jöns; Varghese, Oommen P.; Oommen, Oommen P.

Part of RSC Advances, p. 31980-31988, 2017

• DOI for Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
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Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

Todeschi, Maria R.; El Backly, Rania M.; Varghese, Oommen P.; Hilborn, Jöns et al.

Part of Regenerative Medicine, p. 525-539, 2017

• DOI for Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Gurav, Deepanjali; Varghese, Oommen P.; Hamad, Osama A.; Nilsson, Bo et al.

Part of Chemical Communications, p. 966-969, 2016

• DOI for Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Oommen, Oommen Podiyan; Duehrkop, Claudia; Nilsson, Bo; Hilborn, Jöns et al.

Part of ACS Applied Materials and Interfaces, p. 20614-20624, 2016

• DOI for Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Varghese, Oommen P.; Liu, Jianping; Sundaram, Karthi; Hilborn, Jöns et al.

Part of Biomaterials Science, p. 1310-1313, 2016

• DOI for Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

2 '-N-Guanidino, 4 '-C-ethylene bridged thymidine (GENA-T) modified oligonucleotide exhibits triplex formation with excellent enzymatic stability

Barman, Jharna; Gurav, Deepanjali; Oommen, Oommen Podiyan; Varghese, Oommen P.

Part of RSC Advances, p. 12257-12260, 2015

• DOI for 2 '-N-Guanidino, 4 '-C-ethylene bridged thymidine (GENA-T) modified oligonucleotide exhibits triplex formation with excellent enzymatic stability

Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH

Wang, Shujiang; Gurav, Deepanjali; Oommen, Oommen Podiyan; Varghese, Oommen P

Part of Chemistry - A European Journal, p. 5980-5985, 2015

• DOI for Insights into the Mechanism and Catalysis of Oxime Coupling Chemistry at Physiological pH

Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

Yan, Hongji; Podiyan, Oommen; Yu, Di; Hilborn, Jöns et al.

Part of Advanced Functional Materials, p. 3907-3915, 2015

• DOI for Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

Tailored Doxorubicin-Hyaluronan Conjugate as a Potent Anticancer Glyco-Drug: An Alternative to Prodrug Approach

Podiyan, Oommen; Garousi, Javad; Sloff, Marije; Varghese, Oommen

Part of Macromolecular Bioscience, p. 327-333, 2014

• DOI for Tailored Doxorubicin-Hyaluronan Conjugate as a Potent Anticancer Glyco-Drug: An Alternative to Prodrug Approach

Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells

Yang, Hsiao-yin; Vonk, Lucienne A.; Licht, Ruud; van Boxtel, Antonetta M. G. et al.

Part of European Journal of Pharmaceutical Sciences, p. 35-44, 2014

• DOI for Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells

Smart Design of Stable Extracellular Matrix Mimetic Hydrogel: Synthesis, Characterization, and In Vitro and In Vivo Evaluation for Tissue Engineering

Oommen, Oommen P.; Wang, Shujiang; Kisiel, Marta; Sloff, Marije et al.

Part of Advanced Functional Materials, p. 1273-1280, 2013

• DOI for Smart Design of Stable Extracellular Matrix Mimetic Hydrogel: Synthesis, Characterization, and In Vitro and In Vivo Evaluation for Tissue Engineering

PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties

Rahman, Cheryl V.; Kuhn, Gisela; White, Lisa J.; Kirby, Giles T. S. et al.

Part of Journal of Biomedical Materials Research. Part B - Applied biomaterials, p. 648-655, 2013

• DOI for PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties

Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor

Wang, Shujiang; Oommen, Oommen P.; Yan, Hongji; Varghese, Oommen P.

Part of Biomacromolecules, p. 2427-2432, 2013

• DOI for Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor

Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.

Kisiel, Marta; Ventura, Manuela; Podiyan, Oommen; George, Anu et al.

Part of Journal of Controlled Release, p. 646-653, 2012

• DOI for Critical assessment of rhBMP-2 mediated bone induction: An in vitro and in vivo evaluation.

Minimally invasive mandibular bone augmentation using injectable hydrogels

Martinez-Sanz, Elena; Varghese, Oommen; Kisiel, Marta; Engstrand, Thomas et al.

Part of Journal of Tissue Engineering and Regenerative Medicine, 2012

• DOI for Minimally invasive mandibular bone augmentation using injectable hydrogels

Injectable hyaluronic acid hydrogel for bone tissue engineering

Varghese, Oommen P.; Podiyan, Oommen; Wang, S; Kisiel, Marta et al.

Part of European Cells & Materials, p. 2, 2012

Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation

Martinez-Sanz, Elena; Ossipov, Dmitri A.; Hilborn, Jöns; Larsson, Sune et al.

Part of Journal of Controlled Release, p. 232-240, 2011

• DOI for Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation

Functionalization of Hyaluronic Acid with Chemoselective Groups via a Disulfide-Based Protection Strategy for In Situ Formation of Mechanically Stable Hydrogels

Ossipov, Dmitri A.; Piskounova, Sonya; Varghese, Oommen P.; Hilborn, Jöns

Part of Biomacromolecules, p. 2247-2254, 2010

• DOI for Functionalization of Hyaluronic Acid with Chemoselective Groups via a Disulfide-Based Protection Strategy for In Situ Formation of Mechanically Stable Hydrogels

Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions

Ossipov, Dmitri A.; Yang, Xia; Varghese, Oommen; Kootala, Sujit et al.

Part of Chemical Communications, p. 8368-8370, 2010

• DOI for Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions

Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel

Varghese, Oommen P.; Kisiel, Marta; Martinez-Sanz, Elena; Ossipov, Dmitri A. et al.

Part of Macromolecular rapid communications, p. 1175-1180, 2010

• DOI for Synthesis of Guanidinium-Modified Hyaluronic Acid Hydrogel

In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach

Varghese, Oommen P.; Sun, Weilun; Hilborn, Jöns; Ossipov, Dmitri A.

Part of Journal of the American Chemical Society, p. 8781-8783, 2009

• DOI for In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach