Lanekoff Group
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Biosurface and imaging mass spectrometry
Our group works on developing analytical tools for the detection, characterization, and quantification of small molecules in biological fluids, thin tissue sections, and cells, using mass spectrometry. Our main focus is imaging mass spectrometry and surface analysis, where we try to develop techniques to detect spatial differences in the presence of different molecules on biological surfaces such as thin tissue sections. We are also developing mass spectrometric techniques for chemical analysis of individual cells with the aim of being able to distinguish between diseased and healthy cells in the future.
Publications
Part of International Journal of Molecular Sciences, 2024
- DOI for Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome: A Nano-DESI MS Metabolomics and Shotgun Proteomics Study
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Part of Electrophoresis, p. 387-394, 2023
- DOI for Surface sampling capillary electrophoresis–mass spectrometry for a direct chemical characterization of tissue and blood samples
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Part of Scientific Reports, 2023
- DOI for Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics
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Ischemic Stroke Causes Disruptions in the Carnitine Shuttle System
Part of Metabolites, 2023
- DOI for Ischemic Stroke Causes Disruptions in the Carnitine Shuttle System
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Part of Analytical Chemistry, p. 11589-11595, 2023
- DOI for Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques
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Part of Journal of the American Society for Mass Spectrometry, p. 2341-2349, 2023
- DOI for Identification and Imaging of Prostaglandin Isomers Utilizing MS3 Product Ions and Silver Cationization
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Part of Analytical Chemistry, p. 17843-17850, 2023
- DOI for Revealing Structure and Localization of Steroid Regioisomers through Predictive Fragmentation Patterns in Mass Spectrometry Imaging
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Part of Journal of the American Society for Mass Spectrometry, p. 2518-2524, 2023
- DOI for Global and Spatial Metabolomics of Individual Cells Using a Tapered Pneumatically Assisted nano-DESI Probe
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Single cell metabolism: current and future trends
Part of Metabolomics, 2022
Single-cell metabolomics: where are we and where are we going?
Part of Current Opinion in Biotechnology, 2022
- DOI for Single-cell metabolomics: where are we and where are we going?
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Quantitative determination of sn-positional phospholipid isomers in MSn using silver cationization
Part of Analytical and Bioanalytical Chemistry, p. 7473-7482, 2022
- DOI for Quantitative determination of sn-positional phospholipid isomers in MSn using silver cationization
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Part of Vietnam Journal of Food Control, p. 89-103, 2022
Part of Analytical Chemistry, p. 2391-2398, 2022
- DOI for Host-Guest Chemistry for Simultaneous Imaging of Endogenous Alkali Metals and Metabolites with Mass Spectrometry
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Part of Environmental Science and Technology, p. 3096-3105, 2022
A Direct Infusion Probe for Rapid Metabolomics of Low-Volume Samples
Part of Analytical Chemistry, p. 12875-12883, 2022
- DOI for A Direct Infusion Probe for Rapid Metabolomics of Low-Volume Samples
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Part of Analytical and Bioanalytical Chemistry, p. 2735-2745, 2021
- DOI for CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion
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Part of Communications Biology, 2021
- DOI for In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases
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PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
Part of Organs-on-a-Chip, 2020
- DOI for PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
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Part of Journal of the American Society for Mass Spectrometry, p. 2479-2487, 2020
Advances in mass spectrometry based single-cell metabolomics
Part of The Analyst, p. 782-793, 2019
Part of International Journal of Mass Spectrometry, p. 49-57, 2019
Spatially Defined Surface Sampling Capillary Electrophoresis Mass Spectrometry
Part of Analytical Chemistry, p. 7819-7827, 2019
Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging
Part of Analytical and Bioanalytical Chemistry, p. 2809-2816, 2019
- DOI for Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging
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Part of Encyclopedia of Analytical Chemistry, Wiley-VCH Verlagsgesellschaft, 2018
Improving the biocompatibility of PDMS by improving its curing time and temperature
2018
Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems
Part of Advances In Chromatography, Vol 54, p. 43-72, CRC Press, 2018
- DOI for Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems
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Oversampling To Improve Spatial Resolution for Liquid Extraction Mass Spectrometry Imaging
Part of Analytical Chemistry, p. 2451-2455, 2018
Tailoring the biocompatibility of the elastomer PDMS for on-chip applications
2018
Part of Analytical Chemistry, p. 7246-7252, 2018
Profiling and quantifying endogenous molecules in single cells using nano-DESI MS
Part of The Analyst, p. 3639-3647, 2017
Part of The Analyst, p. 3424-3431, 2017
Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS
Part of Journal of Analytical Methods in Chemistry, 2016
Part of The Analyst, p. 3686-3695, 2016
Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques
Part of Analytical Chemistry, p. 52-73, 2016
Part of Scientific Reports, 2016
- DOI for Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site
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PACAP suppresses dry eye signs by stimulating tear secretion
Part of Nature Communications, 2016
- DOI for PACAP suppresses dry eye signs by stimulating tear secretion
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Part of Analytical and Bioanalytical Chemistry, p. 2063-2071, 2015
Towards Adaptive, Streaming Analysis of X-ray Tomography Data
Part of Synchrotron Radiation News, p. 10-14, 2015
- DOI for Towards Adaptive, Streaming Analysis of X-ray Tomography Data
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Part of Methods in molecular biology, p. 99-106, Springer, 2015
Part of Analytical Chemistry, p. 1872-80, 2014
Matrix effects in biological mass spectrometry imaging: identification and compensation
Part of The Analyst, p. 3528-3532, 2014
Part of Analytical Chemistry, p. 9596-9603, 2013
Part of The Analyst, p. 1971-1978, 2013
Part of Analytical Chemistry, p. 882-889, 2013
C60-ToF SIMS imaging of frozen hydrated HeLa cells
Part of Surface and Interface Analysis, p. 302-304, 2013
Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena pyriformis
Part of Surface and Interface Analysis, p. 211-214, 2013
Velo and REXAN – Integrated Data Management and High Speed Analysis for Experimental Facilities
Part of Proceeding IEEE International Conference on E-Science 2012, p. 1-9, 2012
Part of Analytical Chemistry, p. 8351-8356, 2012
Part of Analytical Chemistry, p. 5737-5743, 2012
An in situ fracture device to image lipids in single cells using ToF-SIMS
Part of Surface and Interface Analysis, p. 257-260, 2011