Michael Welsh

Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Welsh, Michael

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response
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The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Wikström, Gerhard; Welsh, Michael

Ingår i Upsala Journal of Medical Sciences, 2022

• DOI för The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship
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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022

• DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
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Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

He, Qi; Jamalpour, Maria; Bergquist, Eric; Anderson, Robin et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis
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The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences

Welsh, Michael

Ingår i International Journal of Molecular Sciences, 2021

• DOI för The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences
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Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro

Jamalpour, Maria; Bergquist, Eric; Welsh, Michael

Ingår i Experimental Cell Research, 2020

• DOI för Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro
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Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

He, Qi; Li, Xiujuan; He, Liqun; Li, Yousheng et al.

Ingår i International Journal of Cancer, s. 2634-2644, 2020

• DOI för Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
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Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Ingår i Cells, 2019

• DOI för Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
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The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

He, Qi; Li, Xiujuan; Singh, Kailash; Luo, Zhengkang et al.

Ingår i Scientific Reports, 2019

• DOI för The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
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Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia

Jamalpour, Maria; Li, Xiujuan; Gustafsson, Karin; Tyner, Jeffrey et al.

Ingår i Tumor Biology, s. 1-13, 2018

• DOI för Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia
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Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
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Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Li, Xiujuan; Singh, Kailash; Luo, Zhengkang; Mejia Cordova, Mariela et al.

Ingår i Oncotarget, s. 18720-18733, 2018

• DOI för Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas
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Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia

Jamalpour, Maria; Li, Xiujuan; Cavelier, Lucia; Gustafsson, Karin et al.

Ingår i Tumor Biology, 2017

• DOI för Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia
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Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Gustafsson, Karin; Welsh, Michael

Ingår i stem cell investigation, 2016

• DOI för Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Claes Hellerström and Cartesian Diver respirometry

Welsh, Michael

Ingår i Upsala Journal of Medical Sciences, s. 77-80, 2016

• DOI för Claes Hellerström and Cartesian Diver respirometry

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Ingår i Blood, s. 2016-2026, 2015

• DOI för Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.

Nikpour, Maryam; Gustafsson, Karin; Vågesjö, Evelina; Seignez, Cedric et al.

Ingår i Acta Physiologica, s. 200-209, 2015

• DOI för Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.
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The role of the Src Homology-2 domain containing protein B (SHB) in β cells

Welsh, Michael; Jamalpour, Maria; Zang, Guangxiang; Åkerblom, Björn

Ingår i Journal of Molecular Endocrinology, 2015

• DOI för The role of the Src Homology-2 domain containing protein B (SHB) in β cells
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Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

Zang, Guangxiang; Gustafsson, Karin; Jamalpour, Maria; Hong, Jongwook et al.

Ingår i BMC Cancer, 2015

• DOI för Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts
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Role of Src homology 2 domain-containing protein B in the regulation of GFR and renal afferent arteriole responsiveness

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Ingår i The FASEB Journal, 2014

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Ingår i Journal of Endocrinology, s. 267-275, 2014

• DOI för Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
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Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis

Gustafsson, Karin; Willebrand, Elsa; Welsh, Michael

Ingår i Immunology, s. 33-41, 2014

• DOI för Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis
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The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease

Gustafsson, Karin; Jamalpour, Maria; Trinh, Camilla; Kharas, Michael G et al.

Ingår i Journal of Hematology & Oncology, s. 45, 2014

• DOI för The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease
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SHB deficient mice display an increased GFR and augmented renal arteriolar contractions to both Adenosine and Ang II

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Ingår i The FASEB Journal, s. 909.14, 2013

The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Ingår i Journal of Internal Medicine, s. 114-127, 2013

• DOI för VEGFA and tumour angiogenesis
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Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Zang, Guangxiang; Christoffersson, Gustaf; Tian, Geng; Harun-Or-Rashid, Mohammad et al.

Ingår i Cellular Signalling, s. 85-92, 2013

• DOI för Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
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The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity

Gustafsson, Karin; Heffner, Garrett; Wenzel, Pamela L.; Curran, Matthew et al.

Ingår i Experimental Cell Research, s. 1852-1864, 2013

• DOI för The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity
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Absence of the Shb adaptor protein accelerates leukemia progression by control of cytokine responses

Gustafsson, Karin; Jamalpour, Maria; Welsh, Michael

Ingår i Experimental Hematology, 2013

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Christoffersson, Gustav; Zang, Guangxiang; Zhuang, Zhen W.; Vågesjö, Evelina et al.

Ingår i Angiogenesis, s. 469-480, 2012

• DOI för Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency
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The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

Welsh, Michael

Ingår i Diabetologia, s. 2092-2095, 2012

• DOI för The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?
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Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Ingår i Molecular Oncology, s. 333-346, 2012

• DOI för Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
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Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Ingår i BMC Immunology, s. 3, 2011

• DOI för Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
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The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Calounova, Gabriela; Livera, Gabriel; Zhang, X-Q; Liu, Kui et al.

Ingår i PLOS ONE, 2010

• DOI för The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Mokhtari, Dariush; Åkerblom, Björn; Mehmeti, Ilir; Wang, Xuan et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 553-557, 2009

• DOI för Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Impaired glucose homeostasis in Shb-/- mice

Åkerblom, Björn; Barg, Sebastian; Calounova, Gabriela; Mokhtari, Dariush et al.

Ingår i Journal of Endocrinology, s. 271-279, 2009

• DOI för Impaired glucose homeostasis in Shb-/- mice

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Ingår i Cancer Research, s. 2141-2148, 2009

• DOI för Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Funa, Nina; Saldeen, Johan; Åkerblom, Björn; Welsh, Michael

Ingår i Differentiation, s. 443-453, 2008

• DOI för Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Funa, Nina; Reddy, Kalpana; Bhandarkar, Sulochana; Kurenova, Elena et al.

Ingår i Journal of Investigative Dermatology, s. 710-716, 2008

• DOI för Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Hägerkvist, Robert; Mokhtari, Dariush; Lindholm, Cecilia; Farnebo, Filip et al.

Ingår i Experimental Cell Research, s. 284-291, 2007

• DOI för Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

A role of FRK in regulation of embryonal pancreatic beta cell formation

Åkerblom, Björn; Annerén, Cecilia; Welsh, Michael

Ingår i Molecular and Cellular Endocrinology, s. 73-78, 2007

• DOI för A role of FRK in regulation of embryonal pancreatic beta cell formation

Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

Annerén, Cecilia; Welsh, Michael; Jansson, Leif

Ingår i American Journal of Physiology. Endocrinology and Metabolism, 2007

• DOI för Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Davoodpour, Padideh; Landström, Maréne; Welsh, Michael

Ingår i BMC Cancer, s. 161, 2007

• DOI för Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Claes Hellerström: a friendly islet explorer

Andersson, Arne; Eriksson, Ulf J.; Jansson, Leif; Sandler, Stellan et al.

Ingår i Diabetologia, 2007

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Kriz, Vitezslav; Mares, Jaroslav; Wentzel, Parri; Funa, Nina S. et al.

Ingår i Developmental Dynamics, s. 2485-2492, 2007

• DOI för Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

Saldeen, Johan; Kriz, Vitezslav; Agren, Nina; Welsh, Michael

Ingår i Biochem Biophys Res Commun, s. 517-24, 2006

A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

Barbu, Andreea R.; Bodin, Birgitta; Welsh, Michael; Jansson, Leif et al.

Ingår i Diabetologia, s. 2388-2391, 2006

• DOI för A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

Kriz, Vitezslav; Ågren, Nina; Lindholm, Cecilia; Lenell, Samuel et al.

Ingår i Journal of Biological Chemistry, s. 34484-34491, 2006

• DOI för The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Ingår i Blood, s. 1877-1886, 2006

• DOI för Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells

Holmqvist, Kristina; Welsh, Michael; Lu, Lingge

Ingår i Cellular Signalling, s. 1433-1438, 2005

• DOI för A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells