Lung-, allergi- och sömnforskning
![En äldre kvinnlig patient blåser i ett mätinstrument medan en sköterska tittar på.](/images/200.7630b4f918f153429f71553/1714067120716/_MG_7631_1932x828.jpg)
Astma, allergier, kroniskt obstruktiv lungsjukdom (KOL) och sömnapné är sjukdomar med stor betydelse för folkhälsan. I vår forskning undersöker vi hur miljöfaktorer påverkar astma och allergier och hur olika överviktsrelaterade sjukdomar som astma, reflux, diabetes och sömnapné hänger ihop. Vi försöker också förbättra prognosen vid KOL genom att studera betydelsen av träning och nutrition.
Beskrivning av vår forskning
Astma är en av våra stora folksjukdomar. Med ökad kunskap om vilken betydelse påverkbara miljöfaktorer som rökning och hemmiljö har, kan det på sikt ge bättre möjligheter att förebygga och minska förekomsten av astma.
Vi ser också att andelen överviktiga ökar i vårt samhälle. Om vi kan få bättre kunskap om hur olika överviktsrelaterade sjukdomar som astma, reflux, sömnapné och diabetes hänger ihop blir det lättare att optimalt behandla personer med fler än en överviktsrelaterad sjukdom.
Allt fler människor i samhället drabbas också av kroniskt obstruktiv lungsjukdom (KOL). För närvarande finns det ingen farmakologisk behandling som avgörande förbättrar prognosen vid KOL. Om vi kan visa att fysisk träning i kombination med nutritionsbehandling och i vissa fall också med tillägg av oxygen ger bättre livskvalité och minskad risk för förnyade sjukhusinläggningar så har vi gjort stora vinster både ur patient- och samhällsperspektiv.
Publikationer
Ingår i eClinicalMedicine, 2024
- DOI för Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study
- Ladda ner fulltext (pdf) av Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study
Disease burden and unmet need for acute allergic reactions - A patient perspective
Ingår i World Allergy Organization Journal, 2024
- DOI för Disease burden and unmet need for acute allergic reactions - A patient perspective
- Ladda ner fulltext (pdf) av Disease burden and unmet need for acute allergic reactions - A patient perspective
Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
Ingår i Laeknabladid, s. 20-27, 2024
- DOI för Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
- Ladda ner fulltext (pdf) av Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
Ingår i BMJ Open, 2024
- DOI för Association between physical activity over a 10-year period and current insomnia symptoms, sleep duration and daytime sleepiness: a European population-based study
- Ladda ner fulltext (pdf) av Association between physical activity over a 10-year period and current insomnia symptoms, sleep duration and daytime sleepiness: a European population-based study
Ingår i BMJ Open Respiratory Research, 2024
- DOI för Internet-delivered cognitive-behaviour therapy for anxiety related to asthma: study protocol for a randomised controlled trial
- Ladda ner fulltext (pdf) av Internet-delivered cognitive-behaviour therapy for anxiety related to asthma: study protocol for a randomised controlled trial
Spirometric patterns in young and middle-aged adults: a 20-year European study
Ingår i Thorax, s. 153-162, 2024
- DOI för Spirometric patterns in young and middle-aged adults: a 20-year European study
- Ladda ner fulltext (pdf) av Spirometric patterns in young and middle-aged adults: a 20-year European study
Ingår i Respiratory Research, 2024
- DOI för Exertional breathlessness related to medical conditions in middle-aged people: the population-based SCAPIS study of more than 25,000 men and women
- Ladda ner fulltext (pdf) av Exertional breathlessness related to medical conditions in middle-aged people: the population-based SCAPIS study of more than 25,000 men and women
2024
Ingår i BMJ Open Respiratory Research, 2024
- DOI för Nocturnal gastro-oesophageal reflux and respiratory symptoms are increased in sleep apnoea: comparison with the general population
- Ladda ner fulltext (pdf) av Nocturnal gastro-oesophageal reflux and respiratory symptoms are increased in sleep apnoea: comparison with the general population
Ingår i Eur J Epidemiol, 2024
Ingår i Cellular and Molecular Biology, s. 45-52, 2024
- DOI för A comparative study of multiple biomarkers levels in complicated versus noncomplicated type 2 diabetic patients
- Ladda ner fulltext (pdf) av A comparative study of multiple biomarkers levels in complicated versus noncomplicated type 2 diabetic patients
Correcting and harmonising the terminology for exhaled gases
Ingår i European Respiratory Journal, 2024
Does allergy decrease with age?
Ingår i REVUE FRANCAISE D ALLERGOLOGIE, 2024
Ingår i Pulmonary Therapy, s. 133-142, 2024
- DOI för Successful Use of Easyhaler® Dry Powder Inhaler in Patients with Chronic Obstructive Pulmonary Disease: Analysis of Peak Inspiratory Flow from Three Clinical Trials
- Ladda ner fulltext (pdf) av Successful Use of Easyhaler® Dry Powder Inhaler in Patients with Chronic Obstructive Pulmonary Disease: Analysis of Peak Inspiratory Flow from Three Clinical Trials
Cardiopulmonary exercise testing and body composition.
Ingår i ERJ open research, 2024
Ingår i Proceedings of the American Thoracic Society online, s. 165-169, 2024
Eliciting a value set for the Swedish Capability-Adjusted Life Years instrument (CALY-SWE)
Ingår i Quality of Life Research, s. 59-72, 2024
- DOI för Eliciting a value set for the Swedish Capability-Adjusted Life Years instrument (CALY-SWE)
- Ladda ner fulltext (pdf) av Eliciting a value set for the Swedish Capability-Adjusted Life Years instrument (CALY-SWE)
Ingår i BMJ open respiratory research, 2024
- DOI för Respiratory symptoms, exacerbations and sleep disturbances are more common among participants with asthma and chronic airflow limitation: an epidemiological study in Estonia, Iceland and Sweden
- Ladda ner fulltext (pdf) av Respiratory symptoms, exacerbations and sleep disturbances are more common among participants with asthma and chronic airflow limitation: an epidemiological study in Estonia, Iceland and Sweden
Ingår i Respiratory Medicine, 2024
- DOI för Gastroesophageal reflux and snoring are related to asthma and respiratory symptoms: Results from a Nordic longitudinal population survey.
- Ladda ner fulltext (pdf) av Gastroesophageal reflux and snoring are related to asthma and respiratory symptoms: Results from a Nordic longitudinal population survey.
Interplay of clinical biomarkers in allergic asthma diagnosis and severity: A case-control study
Ingår i Cellular and Molecular Biology, s. 69-75, 2024
- DOI för Interplay of clinical biomarkers in allergic asthma diagnosis and severity: A case-control study
- Ladda ner fulltext (pdf) av Interplay of clinical biomarkers in allergic asthma diagnosis and severity: A case-control study
Biomarkers of chronic airflow limitation and COPD identified by mass spectrometry
Ingår i ERJ Open Research, 2024
- DOI för Biomarkers of chronic airflow limitation and COPD identified by mass spectrometry
- Ladda ner fulltext (pdf) av Biomarkers of chronic airflow limitation and COPD identified by mass spectrometry
Ingår i Therapeutic Advances in Respiratory Disease, 2024
- DOI för Relationships between symptoms and lung function in asthma and/or chronic obstructive pulmonary disease in a real-life setting: the NOVEL observational longiTudinal studY
- Ladda ner fulltext (pdf) av Relationships between symptoms and lung function in asthma and/or chronic obstructive pulmonary disease in a real-life setting: the NOVEL observational longiTudinal studY
Ingår i Respiratory Medicine, 2024
- DOI för FEV1 and FVC as robust risk factors for cardiovascular disease and mortality: Insights from a large population study
- Ladda ner fulltext (pdf) av FEV1 and FVC as robust risk factors for cardiovascular disease and mortality: Insights from a large population study
Occupational Dust Exposure as a Risk Factor for Developing Lung Function Impairment
Ingår i Journal of Occupational and Environmental Medicine, 2024
- DOI för Occupational Dust Exposure as a Risk Factor for Developing Lung Function Impairment
- Ladda ner fulltext (pdf) av Occupational Dust Exposure as a Risk Factor for Developing Lung Function Impairment
Birth weight, ideal cardiovascular health metrics in adulthood, and incident cardiovascular disease
Ingår i Chinese Medical Journal, s. 1160-1168, 2024
Ingår i Circulation, 2024
Frailty, genetic predisposition, and incident atrial fibrillation
Ingår i European Heart Journal, s. 1281-1283, 2024
Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults
Ingår i Sleep Medicine, s. 34-40, 2024
- DOI för Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults
- Ladda ner fulltext (pdf) av Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults
Ingår i Sleep, 2024
Ingår i ERJ Open Research, 2024
- DOI för Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients
- Ladda ner fulltext (pdf) av Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients
Ingår i BMC Medicine, 2024
- DOI för Assessing the impact of type 2 diabetes on mortality and life expectancy according to the number of risk factor targets achieved: an observational study
- Ladda ner fulltext (pdf) av Assessing the impact of type 2 diabetes on mortality and life expectancy according to the number of risk factor targets achieved: an observational study
Ingår i International Journal of Epidemiology, 2024
Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis
Ingår i Biomedicines, 2024
- DOI för Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis
- Ladda ner fulltext (pdf) av Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis
Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
Ingår i Diabetes/Metabolism Research Reviews, 2024
- DOI för Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
- Ladda ner fulltext (pdf) av Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
Cardiovascular health, sleeping duration, and risk of mortality in current and former smokers
Ingår i NMCD. Nutrition Metabolism and Cardiovascular Diseases, s. 1257-1266, 2024
Immune-mediated diseases and risk of incident cardiovascular diseases: a prospective cohort study
Ingår i Rheumatology, s. 706-714, 2024
Ingår i Nitric oxide, s. 60-66, 2024
Ingår i Cellular and Molecular Biology, s. 81-91, 2023
- DOI för TGFβ1, SMAD2, CTNNβ1, and Wnt3a gene mutational status and serum concentrations in individuals with non-small cell lung cancer
- Ladda ner fulltext (pdf) av TGFβ1, SMAD2, CTNNβ1, and Wnt3a gene mutational status and serum concentrations in individuals with non-small cell lung cancer
The role of inflammatory and remodelling biomarkers in patients with non-small cell lung cancer
Ingår i Central European Journal of Immunology, s. 330-337, 2023
- DOI för The role of inflammatory and remodelling biomarkers in patients with non-small cell lung cancer
- Ladda ner fulltext (pdf) av The role of inflammatory and remodelling biomarkers in patients with non-small cell lung cancer
Ingår i Health Science Reports, 2023
- DOI för Burden and risk factors of chronic respiratory diseases in Nepal, 1990-2019: An analysis of the global burden of diseases study
- Ladda ner fulltext (pdf) av Burden and risk factors of chronic respiratory diseases in Nepal, 1990-2019: An analysis of the global burden of diseases study
Pharmacological treatment of asthma in Sweden from 2005 to 2015.
Ingår i Journal of Asthma, s. 1-9, 2023
Ingår i Sleep Medicine, s. 219-225, 2023
- DOI för What do women mean by poor sleep?: A large population-based sample with polysomnographical indicators, inflammation, fatigue, depression, and anxiety
- Ladda ner fulltext (pdf) av What do women mean by poor sleep?: A large population-based sample with polysomnographical indicators, inflammation, fatigue, depression, and anxiety
Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 2959-2968, 2023
- DOI för Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients
- Ladda ner fulltext (pdf) av Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients
Cohort Profile: Burden of Obstructive Lung Disease (BOLD) study
Ingår i International Journal of Epidemiology, 2023
- DOI för Cohort Profile: Burden of Obstructive Lung Disease (BOLD) study
- Ladda ner fulltext (pdf) av Cohort Profile: Burden of Obstructive Lung Disease (BOLD) study
Ingår i Environmental Science and Technology, s. 11750-11766, 2023
- DOI för Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants
- Ladda ner fulltext (pdf) av Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants
Diagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts
Ingår i npj Primary Care Respiratory Medicine, 2023
- DOI för Diagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts
- Ladda ner fulltext (pdf) av Diagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts
Ingår i Chest, s. 503-516, 2023
- DOI för OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study
- Ladda ner fulltext (pdf) av OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study
Ingår i Journal of Clinical Sleep Medicine (JCSM), s. 573-579, 2023
Ingår i Respiratory Medicine, 2023
- DOI för Breathlessness and exercise performance to predict mortality in long-term oxygen therapy: The population - based DISCOVERY study
- Ladda ner fulltext (pdf) av Breathlessness and exercise performance to predict mortality in long-term oxygen therapy: The population - based DISCOVERY study
Ingår i Clinical and Translational Allergy, 2023
- DOI för Allergic sensitisation and type-2 inflammation is associated with new-onset and persistent allergic disease
- Ladda ner fulltext (pdf) av Allergic sensitisation and type-2 inflammation is associated with new-onset and persistent allergic disease