Cardiology
![Two doctors in protective gear operating on a patient.](/images/200.3198dce818f28e9f7c85ecc/1714403735340/PCI-labbet_K3A7212_1932x828.jpg)
Cardiovascular disease is the most common cause of death and has the highest costs for drug treatment in Sweden. For more than 25 years, the Cardiology research group has been a national centre for research and development in coronary artery disease and its complications, and in recent years stroke prevention during atrial fibrillation.
Description of our research
The research includes register based studies, cell biology research and large clinical trials with patients and healthy controls from many countries.
We aim to improve the treatment and management for the individual patient. We work in the following areas:
- Disease prevalence and mechanisms of disease throughepidemiologic studies of registries and cohort and pathophysiology studies.
- Diagnosis, risk assessment and precision medicine through biomarker studies and studies on imaging based diagnosis.
- Assessment of old (and new) therapies through international clinical trials, independent registry based randomized clinical trials as well as observational registry- and cohort studies.
- Implementation of new therapies through observational registry studies.
Publications
Symptoms during pregnancy in primiparous women with congenital heart disease
Part of Scandinavian Cardiovascular Journal, 2024
- DOI for Symptoms during pregnancy in primiparous women with congenital heart disease
- Download full text (pdf) of Symptoms during pregnancy in primiparous women with congenital heart disease
Part of Structural Heart, 2024
- DOI for Characteristics and Outcomes of Patients Receiving a Second Rescue Valve During Transcatheter Aortic Valve Implantation
- Download full text (pdf) of Characteristics and Outcomes of Patients Receiving a Second Rescue Valve During Transcatheter Aortic Valve Implantation
Part of Acta Obstetricia et Gynecologica Scandinavica, 2024
Temporal biomarker concentration patterns during the early course of acute coronary syndrome
Part of Clinical Chemistry and Laboratory Medicine, p. 1167-1176, 2024
- DOI for Temporal biomarker concentration patterns during the early course of acute coronary syndrome
- Download full text (pdf) of Temporal biomarker concentration patterns during the early course of acute coronary syndrome
Part of Eur J Epidemiol, 2024
Part of Open heart, 2024
- DOI for Major bleeding in patients with atrial fibrillation treated with apixaban versus warfarin in combination with amiodarone: nationwide cohort study
- Download full text (pdf) of Major bleeding in patients with atrial fibrillation treated with apixaban versus warfarin in combination with amiodarone: nationwide cohort study
Analysis of plasma metabolomes from 11 309 subjects in five population-based cohorts.
Part of Scientific Reports, p. 8933, 2024
Part of Journal of the American Heart Association, 2024
- DOI for Repeated Measurement of the Novel Atrial Biomarker BMP10 (Bone Morphogenetic Protein 10) Refines Risk Stratification in Anticoagulated Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial
- Download full text (pdf) of Repeated Measurement of the Novel Atrial Biomarker BMP10 (Bone Morphogenetic Protein 10) Refines Risk Stratification in Anticoagulated Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial
Part of British Journal of Sports Medicine, 2024
- DOI for Physical fitness in male adolescents and atherosclerosis in middle age: a population-based cohort study
- Download full text (pdf) of Physical fitness in male adolescents and atherosclerosis in middle age: a population-based cohort study
Breastfeeding in primiparous women with congenital heart disease: a register study
Part of International Breastfeeding Journal, 2024
- DOI for Breastfeeding in primiparous women with congenital heart disease: a register study
- Download full text (pdf) of Breastfeeding in primiparous women with congenital heart disease: a register study
Part of Scandinavian Cardiovascular Journal, 2024
- DOI for Self-rated health in primiparous women with congenital heart disease before, during and after pregnancy: A register study
- Download full text (pdf) of Self-rated health in primiparous women with congenital heart disease before, during and after pregnancy: A register study
Time to childbirth and assisted reproductive treatment in women with congenital heart disease
Part of Open heart, 2024
- DOI for Time to childbirth and assisted reproductive treatment in women with congenital heart disease
- Download full text (pdf) of Time to childbirth and assisted reproductive treatment in women with congenital heart disease
Part of Diabetologia, 2024
Part of European Journal of Cardiovascular Nursing, 2024
Part of Europace, 2024
- DOI for Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference
- Download full text (pdf) of Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference
Part of Scandinavian Journal of Gastroenterology, p. 425-432, 2024
- DOI for Tofacitinib real-world experience in ulcerative colitis in Finland (FinTofUC): a retrospective non-interventional multicenter patient chart data study
- Download full text (pdf) of Tofacitinib real-world experience in ulcerative colitis in Finland (FinTofUC): a retrospective non-interventional multicenter patient chart data study
An association between heart rate variability and incident heart failure in an elderly cohort
Part of Clinical Cardiology, 2024
- DOI for An association between heart rate variability and incident heart failure in an elderly cohort
- Download full text (pdf) of An association between heart rate variability and incident heart failure in an elderly cohort
Optimizing warfarin dosing for patients with atrial fibrillation using machine learning
Part of Scientific Reports, 2024
- DOI for Optimizing warfarin dosing for patients with atrial fibrillation using machine learning
- Download full text (pdf) of Optimizing warfarin dosing for patients with atrial fibrillation using machine learning
Part of Journal of the American Heart Association, 2024
- DOI for Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial
- Download full text (pdf) of Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial
Part of ESC Heart Failure, p. 44-53, 2024
- DOI for Outcome prediction by myocardial external efficiency from 11C-acetate positron emission tomography in cardiac amyloidosis
- Download full text (pdf) of Outcome prediction by myocardial external efficiency from 11C-acetate positron emission tomography in cardiac amyloidosis
Part of Clinical Kidney Journal, 2024
- DOI for Associations between inflammatory and angiogenic proteomic biomarkers, and cardiovascular events and mortality in relation to kidney function
- Download full text (pdf) of Associations between inflammatory and angiogenic proteomic biomarkers, and cardiovascular events and mortality in relation to kidney function
Thromboembolic and bleeding events after valvular intervention in patients with atrial fibrillation
Part of Open heart, 2024
- DOI for Thromboembolic and bleeding events after valvular intervention in patients with atrial fibrillation
- Download full text (pdf) of Thromboembolic and bleeding events after valvular intervention in patients with atrial fibrillation
Part of Clinical Chemistry and Laboratory Medicine, p. 729-739, 2024
- DOI for Prognostic significance of chronic myocardial injury diagnosed by three different cardiac troponin assays in patients admitted with suspected acute coronary syndrome
- Download full text (pdf) of Prognostic significance of chronic myocardial injury diagnosed by three different cardiac troponin assays in patients admitted with suspected acute coronary syndrome
Part of Upsala Journal of Medical Sciences, 2024
- DOI for A retrospective nationwide analysis of evolocumab use in Sweden and its effect on low-density lipoprotein cholesterol levels
- Download full text (pdf) of A retrospective nationwide analysis of evolocumab use in Sweden and its effect on low-density lipoprotein cholesterol levels
Part of JAMA Network Open, 2024
- DOI for Application of the Universal Definition of Myocardial Infarction in Clinical Practice in Scotland and Sweden
- Download full text (pdf) of Application of the Universal Definition of Myocardial Infarction in Clinical Practice in Scotland and Sweden
Comorbidities in childhood atopic dermatitis: A population-based study
Part of Journal of the European Academy of Dermatology and Venereology, p. 354-364, 2024
- DOI for Comorbidities in childhood atopic dermatitis: A population-based study
- Download full text (pdf) of Comorbidities in childhood atopic dermatitis: A population-based study
Part of Circulation, p. 290-292, 2024
Part of IJC Heart & Vasculature, 2024
- DOI for Provision of professional interpreters and Heart School attendance for foreign-born compared with native-born myocardial infarction patients in Sweden
- Download full text (pdf) of Provision of professional interpreters and Heart School attendance for foreign-born compared with native-born myocardial infarction patients in Sweden
Part of Implementation Science, 2024
- DOI for The effect of audit and feedback and implementation support on guideline adherence and patient outcomes in cardiac rehabilitation: a study protocol for an open-label cluster-randomized effectiveness-implementation hybrid trial
- Download full text (pdf) of The effect of audit and feedback and implementation support on guideline adherence and patient outcomes in cardiac rehabilitation: a study protocol for an open-label cluster-randomized effectiveness-implementation hybrid trial
Part of European Heart Journal - Quality of Care and Clinical Outcomes, p. 529-536, 2023
Providers, peers and patients. How do physicians?: practice environments affect patient outcomes?
Part of Journal of Health Economics, 2023
The role of imaging in the selection of patients for HFpEF therapy
Part of European Heart Journal Cardiovascular Imaging, p. 1343-1351, 2023
- DOI for The role of imaging in the selection of patients for HFpEF therapy
- Download full text (pdf) of The role of imaging in the selection of patients for HFpEF therapy
Part of European Heart Journal - Quality of Care and Clinical Outcomes, p. 609-620, 2023
- DOI for Data standards for atrial fibrillation/flutter and catheter ablation: The European Unified Registries for Heart Care Evaluation and Randomized Trials (EuroHeart)
- Download full text (pdf) of Data standards for atrial fibrillation/flutter and catheter ablation: The European Unified Registries for Heart Care Evaluation and Randomized Trials (EuroHeart)
Plasma angiopoietin-2 and its association with heart failure in patients with atrial fibrillation
Part of Europace, 2023
- DOI for Plasma angiopoietin-2 and its association with heart failure in patients with atrial fibrillation
- Download full text (pdf) of Plasma angiopoietin-2 and its association with heart failure in patients with atrial fibrillation
Outcomes of patients with atrial fibrillation and ischemic stroke while on oral anticoagulation
Part of European Heart Journal, p. 1807-1814, 2023
Part of Atherosclerosis, p. 46-54, 2023
- DOI for Body weight at age 20 and in midlife is more important than weight gain for coronary atherosclerosis: Results from SCAPIS
- Download full text (pdf) of Body weight at age 20 and in midlife is more important than weight gain for coronary atherosclerosis: Results from SCAPIS
Part of Circulation, p. 1207-1219, 2023
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Part of American Journal of Human Genetics, p. 284-299, 2023
Part of Scientific Reports, 2023
- DOI for Association between high-sensitivity C-reactive protein and coronary atherosclerosis in a general middle-aged population
- Download full text (pdf) of Association between high-sensitivity C-reactive protein and coronary atherosclerosis in a general middle-aged population
A machine learning based approach to identify carotid subclinical atherosclerosis endotypes
Part of Cardiovascular Research, p. 2594-2606, 2023
Part of Journal of Cardiovascular Translational Research, p. 244-254, 2023
- DOI for Screening for Biomarkers Associated with Left Ventricular Function During Follow-up After Acute Coronary Syndrome
- Download full text (pdf) of Screening for Biomarkers Associated with Left Ventricular Function During Follow-up After Acute Coronary Syndrome
Part of European Heart Journal - Cardiovascular Pharmacotherapy, p. 399-400, 2023
Part of Cardiovascular Research, p. 1596-1605, 2023
Part of HEART RHYTHM O2, p. 200-206, 2023
- DOI for Prognostic value of early sustained ventricular arrhythmias in ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention: A substudy of VALIDATE-SWEDEHEART trial
- Download full text (pdf) of Prognostic value of early sustained ventricular arrhythmias in ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention: A substudy of VALIDATE-SWEDEHEART trial
Part of European Journal of Heart Failure, p. 2107-2129, 2023
- DOI for Interaction of heart failure and stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis
- Download full text (pdf) of Interaction of heart failure and stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis
Part of Scientific Reports, 2023
- DOI for Management and outcome trends in type 2 myocardial infarction: an investigation from the SWEDEHEART registry
- Download full text (pdf) of Management and outcome trends in type 2 myocardial infarction: an investigation from the SWEDEHEART registry
Part of Clinical Chemistry and Laboratory Medicine, p. 380-387, 2023
- DOI for Differences between high-sensitivity cardiac troponin T and I in stable populations: underlying causes and clinical implications
- Download full text (pdf) of Differences between high-sensitivity cardiac troponin T and I in stable populations: underlying causes and clinical implications
Part of EuroIntervention, p. 464-+, 2023
Differences between cardiac troponin I vs. T according to the duration of myocardial ischaemia
Part of European Heart Journal, p. 355-363, 2023
Part of Journal of the American College of Cardiology, p. 1343-1359, 2023