Neurology
![Group photo of the staff in the research group in neurology.](/images/200.7630b4f918f153429f71219/1714063980507/Gruppbild_221216_1932x828.jpg)
The research activity at the unit of neurology is strongly patient-oriented. Scientific questions arise from daily clinical practice and are solved by means of clinical / interventional studies and translational studies using biobank material.
Description of our research
Research fields include common neurological diseases such as epilepsy, movement disorders, acute stroke and multiple sclerosis but also sleep disorders, like narcolepsy, and more rare disorders like neurogenetic disorders, for example Huntington’s disease, and low-grade gliomas. Scientific fields like disturbances in the autonomic nervous system have been acknowledged here, and the development of treatments, have led to successful achievements of our unit.
A common focus is ”Neurotherapy”, a field where our unit for a long time achieved a strong position for developing treatments against neurological disease. Such examples are pharmacotherapy administered with pump in Parkinson’s disease, epilepsy surgery and hematopoietic stem cell transplantation (HSCT) against MS, further advanced imaging diagnostics in the mapping of brain tumours, and shunt operations in normal pressure hydrocephalus (NPH).
Research projects
- Huntington's disease and other neurogenetic diseases
- ALS and other motor neurone diseases
- Epilepsy
- MS and other neuroinflammatory diseases
- Normal pressure hydrocephalus and other corpuscular circulation disorders
- Parkinson's disease and other movement disorders
- Stroke and other cerebrovascular diseases
Publications
Part of iScience, p. 110036-110036, 2024
Part of Journal of the Neurological Sciences, 2024
- DOI for Cerebrospinal fluid glial fibrillary acidic protein, in contrast to amyloid beta protein, is associated with disease symptoms in Huntington's disease
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Part of Multiple Sclerosis and Related Disorders, 2024
- DOI for Cerebrospinal fluid mtDNA concentrations are increased in multiple sclerosis and were normalized after intervention with autologous hematopoietic stem cell transplantation
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Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
Part of Journal of Clinical Medicine, 2024
- DOI for Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
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Part of Physica medica (Testo stampato), 2024
- DOI for Comparison of quantitative [11C]PE2I brain PET studies between an integrated PET/MR and a stand-alone PET system
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Evoked potentials after autologous hematopoietic stem cell transplantation for multiple sclerosis
Part of Multiple Sclerosis and Related Disorders, 2024
- DOI for Evoked potentials after autologous hematopoietic stem cell transplantation for multiple sclerosis
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Part of International Journal of Laboratory Hematology, p. 42-49, 2024
- DOI for Extracellular vesicles in plasma and cerebrospinal fluid in patients with COVID-19 and neurological symptoms
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Habitual short sleepers with pre-existing medical conditions are at higher risk of Long COVID
Part of Journal of Clinical Sleep Medicine (JCSM), p. 111-119, 2024
Part of Journal of Neurology, Neurosurgery and Psychiatry, p. 125-133, 2024
- DOI for Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden: an observational cohort study
- Download full text (pdf) of Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden: an observational cohort study
Part of BMC Neurology, 2024
- DOI for Large variations in atrial fibrillation screening practice after ischemic stroke and transient ischemic attack in Sweden: a survey study
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Reduced long-term mortality after successful resective epilepsy surgery: a population-based study
Part of Journal of Neurology, Neurosurgery and Psychiatry, p. 249-255, 2024
- DOI for Reduced long-term mortality after successful resective epilepsy surgery: a population-based study
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Part of Journal of Neurosurgery, p. 1493-1500, 2024
- DOI for Volumetric effect of shunt adjustments in normal pressure hydrocephalus: a randomized, double-blind trial
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A comprehensive diagnostic approach in suspected neurosarcoidosis
Part of Scientific Reports, 2023
- DOI for A comprehensive diagnostic approach in suspected neurosarcoidosis
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Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis
Part of Journal of Clinical Medicine, 2023
- DOI for Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis
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Part of PLOS ONE, 2023
- DOI for Anti-Müllerian hormone and pregnancy after autologous hematopoietic stem cell transplantation for multiple sclerosis
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Part of Fluids and Barriers of the CNS, 2023
- DOI for Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure hydrocephalus
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Part of BMC Public Health, 2023
- DOI for Associations between changes in habitual sleep duration and lower self-rated health among COVID-19 survivors: findings from a survey across 16 countries/regions
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Part of Frontiers in Genetics, 2023
- DOI for Case report: a novel deep intronic splice-altering variant in DMD as a cause of Becker muscular dystrophy
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Part of Brain Communications, 2023
- DOI for Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis
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Part of European Journal of Neurology, p. 3256-3264, 2023
- DOI for Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome
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Part of Neurology, 2023
- DOI for Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug-Resistant Epilepsy in the MORE Multicenter Patient Registry
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Part of Journal of Rehabilitation Medicine, 2023
- DOI for Development of a Swedish short version of the Montreal Cognitive Assessment for cognitive screening in patients with stroke
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Early-onset hereditary isolated non-neurogenic orthostatic hypotension in a Swedish family
Part of Clinical Autonomic Research, p. 421-432, 2023
- DOI for Early-onset hereditary isolated non-neurogenic orthostatic hypotension in a Swedish family
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Experiences in implementing immunopsychiatry in real life
Part of Journal of Affective Disorders Reports, 2023
- DOI for Experiences in implementing immunopsychiatry in real life
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Part of Journal of the Neurological Sciences, 2023
- DOI for Genetic screening for Huntington disease phenocopies in Sweden: A tertiary center case series focused on short tandem repeat (STR) disorders
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Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis in Sweden
2023
Image-derived input functions from dynamic O-15-water PET scans using penalised reconstruction
Part of EJNMMI Physics, 2023
- DOI for Image-derived input functions from dynamic O-15-water PET scans using penalised reconstruction
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Immune response in blood before and after epileptic and psychogenic non-epileptic seizures
Part of Heliyon, 2023
- DOI for Immune response in blood before and after epileptic and psychogenic non-epileptic seizures
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Part of PLOS ONE, 2023
- DOI for Inventory study of an early pandemic COVID-19 cohort in South-Eastern Sweden, focusing on neurological manifestations
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Part of Fluids and Barriers of the CNS, 2023
- DOI for Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases
- Download full text (pdf) of Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases
Part of Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, p. 727-735, 2023
- DOI for Living with a parent with ALS: adolescents' need for professional support from the adolescents' and the parents' perspectives
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Part of BMC Geriatrics, 2023
- DOI for Longitudinal neuropsychological trajectories in idiopathic normal pressure hydrocephalus: a population-based study
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Long-term follow up of patients with WHO grade 2 oligodendroglioma.
Part of Journal of Neuro-Oncology, p. 65-74, 2023
Meningioma classification by immunohistochemistry: A replicability study
Part of BRAIN AND SPINE, 2023
- DOI for Meningioma classification by immunohistochemistry: A replicability study
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Part of Nutrition and Cancer, p. 112-122, 2023
- DOI for Methodological Approaches to Ketogenic Dietary Treatments in Glioma Patients from a Nutritional Point of View
- Download full text (pdf) of Methodological Approaches to Ketogenic Dietary Treatments in Glioma Patients from a Nutritional Point of View
Part of BMJ Open, 2023
- DOI for Multicentre, national, investigator-initiated, randomised, parallel-group, register-based superiority trial to compare extended ECG monitoring versus standard ECG monitoring in elderly patients with ischaemic stroke or transient ischaemic attack and the effect on stroke, death and intracerebral bleeding: the AF SPICE protocol
- Download full text (pdf) of Multicentre, national, investigator-initiated, randomised, parallel-group, register-based superiority trial to compare extended ECG monitoring versus standard ECG monitoring in elderly patients with ischaemic stroke or transient ischaemic attack and the effect on stroke, death and intracerebral bleeding: the AF SPICE protocol
Part of European Journal of Neurology, p. 3142-3148, 2023
- DOI for Myoclonus in patients with COVID-19: Findings of autoantibodies against brain structures in cerebrospinal fluid
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Part of Palliative & Supportive Care, 2023
- DOI for Pain in patients with motor neuron disease: Variation of pain and association with disease severity, health-related quality of life and depression – A longitudinal study
- Download full text (pdf) of Pain in patients with motor neuron disease: Variation of pain and association with disease severity, health-related quality of life and depression – A longitudinal study
Part of BMC Medical Ethics, 2023
- DOI for Patients accept therapy using embryonic stem cells for Parkinson's disease: a discrete choice experiment
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Part of Translational Psychiatry, p. 32, 2023
- DOI for Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals.
- Download full text (pdf) of Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals.
Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy
Part of Brain, p. 1065-1074, 2023
Physical Activity Trajectories and Functional Recovery After Acute Stroke Among Adults in Sweden
Part of JAMA Network Open, 2023
- DOI for Physical Activity Trajectories and Functional Recovery After Acute Stroke Among Adults in Sweden
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Plasma neurofilament light chain is elevated after transcatheter aortic valve implantation
Part of Cardiology, p. 478-483, 2023
- DOI for Plasma neurofilament light chain is elevated after transcatheter aortic valve implantation
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Part of Journal of Neurology, p. 3315-3328, 2023
Part of Lancet Neurology, p. 117-126, 2023
Part of Chronobiology International, p. 114-122, 2023
Part of Journal of Sleep Research, 2023
- DOI for Sleep symptoms are essential features of long-COVID - Comparing healthy controls with COVID-19 cases of different severity in the international COVID sleep study (ICOSS-II)
- Download full text (pdf) of Sleep symptoms are essential features of long-COVID - Comparing healthy controls with COVID-19 cases of different severity in the international COVID sleep study (ICOSS-II)
Part of Trials, 2023
- DOI for Study protocol for a randomized, controlled, multicentre, pragmatic trial with Rehabkompassen®-a digital structured follow-up tool for facilitating patient-tailored rehabilitation in persons after stroke
- Download full text (pdf) of Study protocol for a randomized, controlled, multicentre, pragmatic trial with Rehabkompassen®-a digital structured follow-up tool for facilitating patient-tailored rehabilitation in persons after stroke
Part of Journal of the Neurological Sciences, 2023
- DOI for Symptoms of anxiety and depression in patients with amyotrophic lateral sclerosis and their relatives during the disease trajectory
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The association of insomnia with long COVID: An international collaborative study (ICOSS-II)
Part of Sleep Medicine, p. 216-222, 2023