Epidemiology of diabetes complications

To understand the incidence and prevalence of diabetes complication will help us tackle the most urgent public health problems to tackle.

Project description

Both type 1 and type 2 diabetes carry increased risks of cardiovascular diseases like heart failure, myocardial infarction, and stroke. However, few direct comparisons between type 1 and type 2 diabetes in terms of risks of complications are available. In nationwide type 1 and type 2 diabetes cohorts in Sweden and Norway, we found that the risks of heart failure and myocardial infarction were higher in middle-aged to older patients with type 1 rather than with type 2 diabetes. The risk of chronic kidney disease was higher at all ages in type 1 patients, instead. Future studies will aim to examine these relationships more closely to understand what factors may be responsible for these observations.

Project members

Co-investigators: Robin Kristófi, Johan Bodegard, (AstraZeneca), Anna Norhammar (KI), Marcus Thuresson (Statisticon), David Nathanson (KI), Thomas Nyström (KI), Kåre I Birkeland (University of Oslo), Jan Eriksson

Chosen publications

Kristófi R, Bodegard J, Norhammar A, Thuresson M, Nathanson D, Nyström T, Birkeland KI, & Eriksson JW. Cardiovascular and Renal Disease Burden in Type 1 Compared With Type 2 Diabetes: A Two-Country Nationwide Observational Study. Diabetes Care 2021 44 1211–1218