Novel biomarkers in MG

We have succeeded in detecting small non-coding RNAs; so-called microRNAs, where the levels of some microRNAs (miR-150-5p, miR-21-5p and miR-30e-5p) were elevated in the blood in different types of MG. Follow-up studies are underway to try to validate these microRNAs in larger cohorts and over time to see if they have prognostic value. The goal is to try to develop individualized treatment for MG patients based on these different microRNAs. We are also developing predictive models to link these microRNAs to a protein profile. Here we have found an inflammatory protein profile that is linked to MG and is now being further validated in an international cohort.