Huntington's disease and other neurogenetic diseases
SHAPE is a population genetics study examining potential health consequences of varying lengths of the CAG repeat in the huntingtin gene by linking genetic data with Swedish health registers.
Project description
One of our research projects aims to identify biomarkers in Huntington's disease. Patients, carriers, and individuals without neurological disease are invited to participate. Symptoms are quantified using assessments to evaluate the potential of biomarkers. The goal is to find markers in blood and cerebrospinal fluid that reflect progression and reveal disease mechanisms.
Project members
Project leader: Valter Niemelä
Co-investigators: Dag Nyholm, Helga Maria Grétarsdóttir, Jimmy Sundblom, Ioannis Kouros